RecruitingPhase 2NCT06801041

TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors


Sponsor

M.D. Anderson Cancer Center

Enrollment

20 participants

Start Date

May 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical research study is to learn about the feasibility, safety, and effects of psilocybin-assisted psychotherapy for cancer survivors with depression and/or anxiety.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study (called TRIPS) is testing whether psilocybin-assisted psychotherapy — a guided therapeutic experience using a psychedelic compound — can help cancer survivors who are dealing with depression, anxiety, PTSD, or grief triggered by their cancer diagnosis. **You may be eligible if...** - You are 18 or older - You have had a solid or blood cancer (not in the brain) and currently show no evidence of disease - Your cancer treatment ended and you've been cancer-free for at least 6 months - You have been diagnosed with a mental health condition (such as anxiety, depression, PTSD, or adjustment disorder) that your doctor believes was caused by the cancer experience **You may NOT be eligible if...** - Your cancer is currently active or in the brain - You have a personal or family history of psychosis or schizophrenia - You are taking certain psychiatric medications that may interact with psilocybin - You have serious heart conditions or uncontrolled high blood pressure Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPsilocybin

Participants will recive treatment by mouth on an outpatient basis.


Locations(1)

The University of Texas M. D. Anderson Cancer Center

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT06801041


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