Relationship Between Aspirin Metabolism and Markers of Metabolic Dysfunction Among Pregnant Persons at Risk of Pre-eclampsia

This study is examining how the body processes aspirin in pregnant women who are at risk of preeclampsia (dangerously high blood pressure during pregnancy), and whether differences in aspirin metabolism are linked to metabolic problems like insulin resistance. **You may be eligible if...** - You are pregnant and less than 16 weeks along - Your doctor has recommended low-dose aspirin to reduce your risk of preeclampsia - You are willing to take aspirin as directed and complete study assessments - You can speak and read English **You may NOT be eligible if...** - You have Type 1 or Type 2 diabetes, or gestational diabetes - You have a platelet disorder or bleeding condition (such as ITP or TTP) - You have an allergy to aspirin or NSAIDs - You have a multiple pregnancy (twins or more) Talk to your doctor to see if this trial is right for you.