RecruitingNot ApplicableNCT06803771

Surveillance of Pancreatic Health After Diabetes Diagnosis

A Randomised Trial to Evaluate the cfDNA Pancreatic Cancer Test (Avantect) in the Early Detection of Pancreatic Cancer in Patients With Newly Diagnosed Diabetes Mellitus

Sponsor

University Hospital Southampton NHS Foundation Trust

Enrollment

15,000 participants

Start Date

May 21, 2025

Study Type

INTERVENTIONAL

Conditions

Diabetes Mellitus Pancreatic Cancer, Adult

Summary

The goal of this interventional study is to evaluate if the novel diagnostic blood test, called Avantect can early detect pancreatic cancer in patients diagnosed with type 2 diabetes within the last 6 months. Participants will: * attend 3 study visits over 12 months time * provide a blood sample at each study visit * complete an anxiety questionnaire at each visit.

Eligibility

Min Age: 50 YearsMax Age: 84 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying whether people newly diagnosed with type 2 diabetes (within the past 6 months) are at higher risk for pancreatic cancer, by doing blood tests and imaging scans to look for early signs of disease. You may be eligible if: you are between 50 and 84 years old; you were recently diagnosed with type 2 diabetes (within the past 180 days); you are willing to give blood samples and undergo MRI or CT scans; and you understand and agree to the study process. You may NOT be eligible if: you were diagnosed with diabetes more than 6 months ago; you have a history of pancreatic cancer, pancreatic tumors, or pancreatitis; you have had certain recent surgeries; you have had another cancer in the past 3 years; you are pregnant or on dialysis; or you have had a recent blood transfusion or organ transplant. Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEAvantect Pancreatic Cancer Test

Avantect test

Locations(31)

Ashfields Primary Care Centre

Sandbach, Cheshire, United Kingdom

Maidstone and Tunbridge Wells NHS Trust

Maidstone, Kent, United Kingdom

Balance Street Health Centre

Uttoxeter, Kent, United Kingdom

Forest Medical Group

Leicester, Leicester Forest East, United Kingdom

South Leicestershire Medical Group

Kibworth Beauchamp, Leicestershire, United Kingdom

Peel Croft Surgery

Burton-on-Trent, Staffordshire, United Kingdom

Kingswinford Medical Practice

Kingswinford, Staffordshire, United Kingdom

Park Medical Centre

Leek, Staffordshire, United Kingdom

Trinity Court Surgery

Stratford-upon-Avon, Staffordshire, United Kingdom

Brockwood Medical Practice

Brockham, Surrey, United Kingdom

Integrated Care Partnership/ The Old Cottage Hospital

Epsom, Surrey, United Kingdom

Warlingham Green Medical Practice

Warlingham, Surrey, United Kingdom

Ashton Medical Group

Ashton-under-Lyne, United Kingdom

Yardley Wood Health Centre

Birmingham, United Kingdom

Bournemouth Research Hub

Bournemouth, United Kingdom

Eastham Group Practice

Bromborough, United Kingdom

Willesden Medical Centre

London, United Kingdom

South Westminster Centre

London, United Kingdom

The Cuckoo Lane Practice

London, United Kingdom

Bodey Medical Centre

Manchester, United Kingdom

Bowland Medical Practice

Manchester, United Kingdom

The Maples Medical Centre

Manchester, United Kingdom

King's Mill Hospital (Sherwood Forest) Research Van

Nottingham, United Kingdom

Portsmouth Research Hub

Portsmouth, United Kingdom

Hazelvalley Family Practice

Rossendale, United Kingdom

Pembroke Centre (Hillingdon)

Ruislip, United Kingdom

Southampton Research Hub (Shirley Research Hub)

Southampton, United Kingdom

Moorgreen Hospital

Southampton, United Kingdom

Civic Centre

Uxbridge, United Kingdom

Quinton Practice

Walsall, United Kingdom

Weymouth Research Hub

Weymouth, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT06803771

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Surveillance of Pancreatic Health After Diabetes Diagnosis

Conditions

Summary

Eligibility

Plain Language Summary

Interventions

Locations(31)

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