Impact of Intraoperative Non-invasive Analgesia Monitoring Using Nociception Level Index on Patient Management
Osoian Cristiana
160 participants
May 18, 2023
INTERVENTIONAL
Conditions
Summary
This prospective randomised clinical trial aims to assess the impact of intraoperative nociception monitoring using NOL on anesthetic management during major abdominal surgery. Additionally, the study will objectively evaluate using NOL how intravenous lidocaine administration, influences opioid requirements and the effect of this multimodal approach on early postoperative outcomes. The investigators hypothesize that NOL-guided intraoperative opioid administration reduces both intraoperative and postoperative opioid use, positively influencing 24-hour outcomes. Furthermore, the addition of intraoperative lidocaine in NOL-guided analgesia may further decrease opioid consumption.
Eligibility
Inclusion Criteria3
- age > 18 years
- ASA score I-III
- surgery for gastric or hepatobiliary or pancreatic neoplasia
Exclusion Criteria14
- pregnancy
- lactation
- neuraxial or regional anesthesia
- chronic treatment with drugs that can influence autonomic nervous system
- diuretics or nitroglycerin administration on the day of surgery
- severe neurological disability
- severe hemodynamic instability
- chronic pain
- chronic opioid treatment
- allergy to any of the study drugs
- severe untreated disease or organ failure
- pacemaker
- emergency surgery
- patient refusal to participate
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Interventions
intravenous lidocaine 10 mg/ml continuous infusion
Intraoperative Nociception Level index monitoring and guided analgesia
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06804434