RecruitingNot ApplicableNCT06804668

Safety and Feasibility of Tele-supervised Home-based Transcranial Direct Current Stimulation in Parkinson's Disease

Sponsor

Brigham and Women's Hospital

Enrollment

6 participants

Start Date

Feb 6, 2025

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

The goal of this clinical trial is to learn whether home-based transcranial direct current stimulation (tDCS) is safe and practical for people aged 40 to 70 years with Parkinson's Disease. The study aims to find out if participants can use the tDCS device at home without serious side effects and whether it is easy for them to use on their own. Participants will first attend an in-person visit to learn how to use the tDCS device. They will then use the device at home once a day for 20 minutes over seven consecutive days. Video calls on days 2 and 3 will provide support and supervision. After each session, participants will complete brief online questionnaires about any side effects and how easy the device was to use. The study will also check if using tDCS at home improves motor symptoms in Parkinson's Disease by using a standard movement assessment.

Eligibility

Min Age: 40 YearsMax Age: 70 Years

Inclusion Criteria1

Patients with the diagnosis of Parkinson's disease, aged between 40 and 70, who provide verbal and written informed consent will be included. Patients should have access to a computer system for video calls and completing the questionnaires, and they must be able to use it.

Exclusion Criteria6

Psychiatric symptoms such as moderate or severe depression
Cranial metal implants
Cardiac pacemaker
Epilepsy, stroke
Substance abuse
Inability to adjust the neoprene cap with the electrodes independently due to movement disturbances

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Interventions

DEVICEtDCS

The intervention involves a home-based, self-administered application of network-targeted, multifocal transcranial direct current stimulation (tDCS) using the Neuroelectrics® StarStim Home-tES device. Participants will apply the tDCS for 20 minutes each day over seven consecutive days. The device is specifically programmed to target a brain network associated with motor symptom improvement in Parkinson's Disease, based on recent research identifying this network through deep brain stimulation studies.