RecruitingNot ApplicableNCT05065151

Understanding Motivation in Parkinson's Patients Through Neurophysiology


Sponsor

University of California, San Francisco

Enrollment

70 participants

Start Date

Oct 30, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Has Parkinson's Disease or Dystonia
  • Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN
  • Has DBS device implanted either bilaterally or unilaterally
  • Male or female
  • More than 1 month post-DBS surgery

Exclusion Criteria4

  • Severe cognitive impairments
  • Has MOCA score below 20
  • Pregnancy
  • Age less than 18 years old

Interventions

OTHERStimulation on

Stimulation from Percept DBS will be on while the patient is playing a decision-making game on a computer-based application.

OTHERStimulation off

Stimulation from Percept DBS will be off while the patient is playing a decision-making game on a computer-based application.

BEHAVIORALDecision Making Task

Patients will be playing a decision making task through a computer-based application.


Locations(1)

University of California San Francisco

San Francisco, California, United States

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NCT05065151


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