RecruitingNCT06809868

Role of Transposable Elements in Septic Immune Aging

Sponsor

University of California, San Francisco

Enrollment

116 participants

Start Date

Feb 14, 2025

Study Type

OBSERVATIONAL

Conditions

Sepsis Sepsis, Septic Shock Sepsis and septic shock Sepsis, Severe Sepsis With Multiple Organ Dysfunction (MOD)Sepsis With Acute Organ Dysfunction Sepsis at Intensive Care Unit Sepsis, Severe Sepsis and Septic Shock

Summary

The goal of this observational study is to learn about how transposable element levels affect the patient outcomes in sepsis. The main questions it aims to answer is: 1. Do transposable elements prematurely age the immune systems of patients with sepsis? 2. Do transposable elements correlate with increased mortality in patients with sepsis in the ICU? 3. Do transposable elements correlate with increased amount of secondary infections in patients with sepsis in the ICU? Participants will have blood drawn from them but will not be subjected to additional interventions.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying RNA and DNA Sequencing for people with sepsis, sepsis with acute organ dysfunction, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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