RecruitingNCT06832293

My MS and My Menstrual Cycle

Measuring MS Symptoms in Relation to Menstrual Cycles: Exploring How MS Symptoms May be Affected at Different Times During a Menstrual Cycle in Females Living With Multiple Sclerosis

Sponsor

University of Alberta

Enrollment

300 participants

Start Date

Feb 19, 2025

Study Type

OBSERVATIONAL

Conditions

Multiple Sclerosis Menstrual Cycle

Summary

The goal of this observational study is to understand how MS symptoms change during different phases of the menstrual cycle in individuals who menstruate living with MS (Multiple Sclerosis). The main questions it aims to answer are: 1. Does fatigue get worse during certain phases of the menstrual cycle? 2. How do symptoms like thinking skills, pain, and mobility change throughout the cycle? Participants will: * Use the My Normative app to track their menstrual cycle and MS symptoms. * Complete symptom check-ins at five points during their cycle for six months. * Answer questions about fatigue, thinking skills, mood, sleep, and other MS symptoms at the start and end of the study. These findings may help researchers better understand MS symptom patterns and improve symptom management.

Eligibility

Sex: FEMALEMin Age: 16 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating how the menstrual cycle affects multiple sclerosis (MS) symptoms. Many women with MS notice their symptoms change at different points in their cycle, but this has not been well studied. Participants will use a smartphone app to track their MS symptoms and cycle over time. **You may be eligible if...** - You have been diagnosed with MS based on current diagnostic criteria - You are 16 years or older - You currently have regular menstrual cycles (21–35 days) - You have not yet entered menopause - You are able to speak English and complete questionnaires - You are comfortable using a smartphone app **You may NOT be eligible if...** - You have been diagnosed with a different central nervous system inflammatory condition such as neuromyelitis optica spectrum disorder (NMOSD) - You are on gender-affirming hormone therapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

University of Calgary

Calgary, Alberta, Canada

University of Alberta

Edmonton, Alberta, Canada

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NCT06832293

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