RecruitingNCT06832436

Atrial Strain in Septic Shock

Assessment of Left And Right Atrial Strain in Septic Shock


Sponsor

Centre Hospitalier Universitaire, Amiens

Enrollment

60 participants

Start Date

Mar 6, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Septic shock is a critical condition associated with high mortality. Transthoracic echocardiography is widely used to evaluate cardiac function and guide treatment. Left and right atrial strain (LAS and RAS) measured via speckle tracking echocardiography have shown prognostic value in cardiovascular diseases. However, differences exist between echocardiographic software, leading to challenges in result comparability. This study aims to compare LAS and RAS measurements between ECHOPAC and UWS software, evaluate AutoStrain technology, and assess reproducibility across observers. The study is non-interventional and will use retrospective echocardiographic data from patients treated for septic shock. The findings will contribute to improving measurement standardization in critically ill patients.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Age: >18 years
  • Adult patients admitted to critical care for septic shock (SEPSIS-3 definition)
  • TTE performed as part of medical management
  • No objection to data usage

Exclusion Criteria7

  • Pregnancy
  • Moderate to severe valvular regurgitation/stenosis (>grade 2)
  • Ventricular or supraventricular tachyarrhythmia (HR >140 bpm) at the time of TTE
  • Poor echogenicity preventing LAS measurement
  • Mechanical circulatory support
  • Pacemaker dependence
  • Patients under guardianship

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Locations(1)

CHRU Amiens

Salouël, France

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NCT06832436


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