RecruitingNot ApplicableNCT06832761

Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial

Secondary Prevention of Dementia in Memory Clinics: Implementation and (Cost-)Effectiveness of an Integrated Lifestyle Intervention

Sponsor

Maastricht University Medical Center

Enrollment

300 participants

Start Date

Jan 27, 2025

Study Type

INTERVENTIONAL

Conditions

Dementia Cognitive Decline Lifestyle Risk Reduction Lifestyle Intervention

Summary

Lifestyle Intervention in the memory clinics of General and academic Hospitals Trial (LIGHT) is a multi-center, randomized, controlled, lifestyle intervention trial among 300 older adults (≥50 years) with subjective cognitive decline (SCD) and mild cognitive impairment (MCI) at risk of dementia. Participants are randomized in a 1:1 ratio to Group A (tailored lifestyle intervention) or Group B (general health advice) for a duration of 12 months. The lifestyle intervention comprises three parts 1) Lifestyle coaching, 2) a voucher program, and 3) online self-management. Group B will receive general health advice.

Eligibility

Min Age: 50 Years

Inclusion Criteria3

≥50 years of age at pre-screening;
Having a diagnosis of SCD or MCI;
Presence of ≥ 2 modifiable risk factors for dementia.

Exclusion Criteria4

Having a diagnosis of dementia;
Insufficient understanding of the Dutch language;
Conditions affecting safe and continuous engagement in the intervention (e.g. under treatment for current malignant diseases, major psychiatric disorders (e.g. major depression, psychosis, bipolar disorder), other conditions preventing co-operation as judged by the local study nurse or consulted physician at the local study site;
Participation in any other research intervention trial at time of pre-screening and throughout the study period.

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Interventions

BEHAVIORALPersonalized lifestyle intervention

The lifestyle intervention in Group A comprises three parts (1) three individual consultations with a trained lifestyle coach, (2) a voucher program to encourage brain healthy activities, and (3) access to an online self-management tool for dementia risk reduction (www.breinzorg.nl).