RecruitingPhase 3NCT06836492

A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors.

A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors: a Single Arm Trial.


Sponsor

Yizhuo Zhang

Enrollment

300 participants

Start Date

Jan 30, 2017

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose is to explore the efficacy and safety of the SYSUCC-RMS regimen for pediatric RMS patients and to explore the impact of concurrent radiotherapy and chemotherapy on the survival rate of low-risk, medium risk, high-risk, and extremely high-risk patients in children.


Eligibility

Min Age: 0 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tracks children and teenagers with rhabdomyosarcoma — a type of cancer that starts in muscle tissue — and divides them into risk groups to compare how well different treatment strategies work based on those risk levels. **You may be eligible if...** - You (or your child) are under 18 years old, any gender - The tumor has been confirmed by tissue biopsy or bone marrow testing - This is the first time receiving treatment for this cancer - Performance status is adequate (ECOG ≤ 2) - Expected survival is more than 8 months - A parent or guardian can provide written informed consent **You may NOT be eligible if...** - There is an underlying immune deficiency disease - There is a second, separate cancer diagnosis at the same time Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

COMBINATION_PRODUCTVAC,VAC/VII,CAV/IE

Low risk: VAC Intermediate risk: VAC/VII High risk: CAV/IE Very high risk: CAV/VIP


Locations(1)

Suying Lu

Guangzhou, Guangdong, China

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NCT06836492


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