RecruitingPhase 1NCT06840678

Home-based Transcranial Static Magnetic Field Stimulation (tSMS) of the Supplementary Motor Area in Parkinson's Disease

Patogénesis Cortical De La Enfermedad De Parkinson: Efectos Corticales Y Corticoestriatales De La Estimulación Transcraneal Por Campo Magnético Estático En Pacientes Con Enfermedad De Parkinson


Sponsor

Fundación de investigación HM

Enrollment

20 participants

Start Date

Oct 1, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This is a pilot open study to test the hypothesis that home-based transcranial static magnetic field stimulation (tSMS) of the supplementary motor area is safe and feasible to modulate corticostriatal activity in patients with Parkinson's disease.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a home-based device that applies static (non-moving, non-electrical) magnetic fields to the head can help improve motor symptoms in people with Parkinson's disease. Unlike transcranial magnetic stimulation (TMS), this device uses permanent magnets and does not generate electrical currents. Participants use the device at home over several weeks, making it convenient and potentially accessible to people who cannot travel frequently to a clinic. **You may be eligible if...** - You have been diagnosed with idiopathic Parkinson's disease (the most common form, not caused by other conditions) - Your motor symptoms (like tremor, stiffness, slowness) respond well to your dopamine medication — at least a 30% improvement on a standard assessment scale (MDS-UPDRS-III) **You may NOT be eligible if...** - You have metal implants in your body that are unsafe near magnets, such as a cardiac pacemaker, deep brain stimulator, or cochlear implant - You have involuntary movements (dyskinesias) caused by your Parkinson's medication - You have other major neurological or psychiatric conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICETranscranial static magnetic field stimulation (tSMS) of the supplementary motor area

Transcranial static magnetic field stimulation (tSMS) is a non-invasive brain stimulation (NIBS) technique that decreases cortical excitability. Static magnetic fields suitable for tSMS are obtained with commercially available neodymium magnets. The investigators will use a cylindrical neodymium magnet of 60 mm diameter and 30 mm of thickness (MAG60r; Neurek SL, Toledo, Spain), which will be applied with south polarity to the supplementary motor area (SMA) using an ergonomic helmet (MAGsv1.1, Neurek SL, Toledo, Spain).


Locations(1)

HM CINAC, Hospital Universitario HM Puerta del Sur, HM Hospitales

Móstoles, Madrid, Spain

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NCT06840678


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