The Effect of Different Risk Factors on the Success Rate of VPT
The Effect of Different Risk Factors on the Success Rate of VPT: an Observational Prospective Cohort Study
Semmelweis University
400 participants
Jun 1, 2024
OBSERVATIONAL
Conditions
Summary
This study aims to evaluate the effectiveness of various vital pulp therapy (VPT) methods, such as direct pulp capping, partial pulpotomy, and total pulpotomy, in maintaining pulp vitality following pulp exposure. It explores the success rates of these treatments compared and investigates co-factors influencing these rates, including age. This prospective cohort study involves patients over 18 with restorable teeth and exposed pulp chambers. Success is measured through clinical and radiological criteria over a follow-up period of up to four years. The study also aims to identify if there's an age threshold affecting the preference for VPT over root canal therapy.
Eligibility
Inclusion Criteria4
- Patients over 18 years of age who have at least one tooth with a pulp chamber that has been opened during a dental procedure or is likely to be opened during restoration of the tooth
- The tooth is responsive to a sensitivity test with cold spray
- The coronal part must be restorable
- The periodontal depth around the tooth should be 0 according to the Dental Practicality Index Periodontal Treatment Need, i.e. the probing depth around the tooth should not be greater than 3.5 mm
Exclusion Criteria9
- Internal/external resorption in the tooth
- If the root development of the tooth is not yet complete or if it is a deciduous tooth
- Absolute isolation cannot be performed during the procedure
- If pulp exposure does not occur even after complete removal of caries
- The crown of the tooth cannot be restored
- Periodontium surrounding tooth affected by moderate/severe marginal periodontitis (probing depth deeper than 3.5 mm)
- Pulp exposure due to traumatic injury
- Baseline radiograph shows signs of severe pulp palcification
- Periapical lesion is around the root (Periapical index of the tooth \>2)
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
After the bleeding has stopped, the cavity is flushed with sterile saline and Biodentine (Septodont, Saint-Maur-des-Fossés, France) is mixed according to the manufacturer's instructions. First it is applied directly to the pulp wound using light pressure, and then the entire cavity is filled with it. One week later the superficial 2-3 mm is removed and replaced it with permanent restoration.
After the bleeding has stopped, the cavity is flushed with sterile saline and MTA+ (Cercamed, Stalowa Wola, Poland) is mixed according to the manufacturer's instructions. First it is applied directly to the pulp wound using light pressure, and after its initial setting the cavity is filled with glass ionomer cement. One week later the glass ionomer cement is removed and replaced it with permanent restoration.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06844448