Irreversible Pulpitis Clinical Trials

8 recruiting

Irreversible Pulpitis Trials at a Glance

25 actively recruiting trials for irreversible pulpitis are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 20 trials, with the heaviest enrollment activity in Cairo, Cairo, and Alcorcón. Lead sponsors running irreversible pulpitis studies include Future University in Egypt, Cairo University, and Postgraduate Institute of Dental Sciences Rohtak.

Browse irreversible pulpitis trials by phase

Treatments under study

About Irreversible Pulpitis Clinical Trials

Looking for clinical trials for Irreversible Pulpitis? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Irreversible Pulpitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Irreversible Pulpitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 25 trials

Recruiting
Phase 4

Intraoral Cryotherapy on Anesthetic Efficacy in Mandibular Incisors

Symptomatic Irreversible Pulpitis (SIP)
Ondokuz Mayıs University98 enrolled1 locationNCT07517367
Recruiting
Not Applicable

Predicting Vital Pulp Treatment Outcomes in Symptomatic Pulpits Using Metabolic Biomarker

Reversible PulpitisPulp Disease, DentalPulpitis+1 more
Abeer Ghalib Abdul-khaliq60 enrolled1 locationNCT07452614
Recruiting
Not Applicable

Short Term Comparative Assessment of MTA and Biodentine in Complete Pulpotomy for Symptomatic Irreversible Pulpitis

Symptomatic Irreversible Pulpitis (SIP)
Dow University of Health Sciences60 enrolled2 locationsNCT07483788
Recruiting
Not Applicable

Postoperative Pain After Root Canal Obturation Using Bioceramic and Calcium Hydroxide Sealers

Symptomatic Irreversible Pulpitis
HITEC-Institute of Medical Sciences50 enrolled1 locationNCT07410780
Recruiting

Do oral steroids or painkillersNon steriodal anti inflammatory drugs (NSAID’S) help dentists numb lower back teeth better in patients with severe toothache?

Acute dental painSymptomatic irreversible pulpitis of mandibular molars
Dr Fawad Ali shah- Khyber college of dentistry60 enrolled1 locationACTRN12626000147381
Recruiting
Not Applicable

Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy

Symptomatic Irreversible PulpitisSymptomatic Irreversible Pulpitis (SIP)
University of Fujairah46 enrolled1 locationNCT07290049
Recruiting
Not Applicable

Evaluation Of Laser Versus Conventional Pulpotomies In Mature Molar Teeth With Irreversible Pulpitis

Irreversible Pulpitis (Toothache)
Rana Hegaz60 enrolled1 locationNCT07287709
Recruiting
Not Applicable

A Randomized Controlled Trial Evaluating Whether Pre-operative Trinase Reduces Post-operative Pain in Patients With Symptomatic Irreversible Pulpitis Compared to Placebo, Using VAS Scores and Analgesic Intake Over 48 Hours.

Endodontic DiseaseSymptomatic Irreversible Pulpitis (SIP)Dental Pain+1 more
Fayoum University182 enrolled1 locationNCT07239505
Recruiting
Not Applicable

The Effect of Three Different Medications on Anesthetic Success and Postoperative Pain

Symptomatic Irreversible Pulpitis
Cairo University120 enrolled2 locationsNCT06298383
Recruiting
Not Applicable

Effect of Apical Third Enlargement to Different Taper and Master Apical Preparation Size on Periapical Healing and Postoperative Pain After Primary Single Sitting Non Surgical Root Canal Treatment

Asymptomatic Irreversible Pulpitis
Postgraduate Institute of Dental Sciences Rohtak270 enrolled1 locationNCT07166679
Recruiting
Not Applicable

Complete Pulpotomy and Root Canal Treatment Patients With Irreversible Pulpitis With Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus (T2DM)Irreversible Pulpitis
Postgraduate Institute of Dental Sciences Rohtak106 enrolled1 locationNCT07163975
Recruiting
Not Applicable

Concerned Growth Factor VS Miniral Trioide Aggregate in Treatment of Mature Permanent Teeth of Children With Symptomatic Irreversible Pulpitis.

Concerned Growth Factor Versus Miniral Trioide Aggregate in Management of Mature Permanent Molar With Irreversible Pulpitis
Minia University200 enrolled1 locationNCT07138287
Recruiting
Not Applicable

Intraligamentary vs Inferior Alveolar Nerve Block for Pulpitis: A Randomized Clinical Trial

Local AnesthesiaSymptomatic Irreversible Pulpitis (SIP)Dental Pain+1 more
Aula Dental Avanzada52 enrolled2 locationsNCT07130760
Recruiting

Bite Force Measurements

Irreversible Pulpitis
Rutgers, The State University of New Jersey112 enrolled1 locationNCT06843525
Recruiting
Not Applicable

The Effect of XP-Endo Finisher Activation of Bioceramic Sealer on Postoperative Pain in Mandibular First Molar With Symptomatic Irreversible Pulpitis

Symptomatic Irreversible Pulpitis
Future University in Egypt30 enrolled1 locationNCT06640231
Recruiting

Effectiveness of Pulpotomy in Symptomatic Permanent Teeth With Deep Caries Lesions

Irreversible PulpitisPulpotomy of Permanent Molars
Universidad Rey Juan Carlos50 enrolled1 locationNCT06918639
Recruiting
Not Applicable

Postoperative Pain After Full Pulpotomy With TheraCal PT, Biodentin, and MTA

Symptomatic Irreversible Pulpitis (SIP)
Cumhuriyet University51 enrolled2 locationsNCT06880471
Recruiting

The Effect of Different Risk Factors on the Success Rate of VPT

Irreversible PulpitisReversible PulpitisPulp Disease, Dental+2 more
Semmelweis University400 enrolled1 locationNCT06844448
Recruiting
Not Applicable

Clinical and Radiographic Assessment of Photobiomodulated MTA Pulpotomy in Immature First Permanent Molars with Irreversible Pulpitis

Irreversible PulpitisDental Caries
Mansoura University72 enrolled1 locationNCT06730360
Recruiting
Not Applicable

The Effect of Eddy Sonic Versus AF Max Activation of Bio-ceramic Sealer on Post-operative Pain in Teeth with Symptomatic Irreversible Pulpitis with Apical Periodontitis

Irreversible Pulpitis with Apical Periodontitis
Future University in Egypt30 enrolled1 locationNCT06640218