Vessel Imaging Using Optical Coherence Tomography for Plaque Morphology and Vessel Fractional Flow Reserve
Medical University of Warsaw
200 participants
Sep 20, 2020
OBSERVATIONAL
Conditions
Summary
The aim of this prospective, investigator-initiated study is to evaluate the diagnostic accuracy and correlations between mopphometric indices: luminal and qualitative parameters assessed by optical coherence tomography (OCT) including minimal lumen area, plaque type, presence of thin cap fibroatheroma and a functional index - angiography based vessel fractional flow reserve (vFFR) among patients with chronic coronary syndrome identified with intermediate grade coronary stenosis.
Eligibility
Inclusion Criteria3
- years or older
- Chronic coronary syndrome defined as presence of chest pain ranked 2-3 in the Canadian Cardiovascular Society classification or positive ischemia test (exercise test, single photon emission tomography (SPECT)
- Intermediate grade coronary stenosis of 40-80% assessed visually in coronary angiography and OCT examination The patient is willing to participate in the study and has provided a written informed consent
Exclusion Criteria9
- Acute coronary syndrome
- Proximal left main lesion
- Ostial right coronary artery lesion
- Bypass of the assessed vessel
- Contraindications for adenosine administration
- Hemodynamic instability
- Heart insufficiency in New York Heart Association (NYHA) class IV scale
- Acute renal insufficiency
- Pregnancy
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Interventions
Optical coherence tomography and vessel fractional flow reserve evaluation of coronary arteries with intermediate to severe stenosis.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06844942