RecruitingNot ApplicableNCT06853288

Effects of Ultra Processed Food on Intestinal Energy Harvest


Sponsor

Columbia University

Enrollment

20 participants

Start Date

Mar 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Ultra processed food is everywhere in modern society and may contain multiple ingredients that affect the way participants' bodies store energy. Some studies have shown that eating a diet high in ultra processed foods leads to weight gain, but these foods have not been studied enough to understand why. Recently, the gut microbiome has become a potential way to measure energy balance in the human body; this is done by measuring how many calories are in the stool. The investigators propose to test a very high ultra-processed food diet where 80% of calories are coming from ultra processed food and a low ultra processed food diet where 20% of the calories are coming from ultra processed food. This study will compare stool sample energy content of the two diets.


Eligibility

Min Age: 25 Years

Inclusion Criteria5

  • BMI 30-40kg/m2
  • weight stable
  • able to download app and willing to use it for duration of study
  • does own grocery shopping
  • otherwise healthy

Exclusion Criteria3

  • pregnancy
  • history of or planned bariatric surgery
  • history of anti obesity medications

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Interventions

BEHAVIORALDiet containing 80% ultra processed foods

Very high ultra-processed food diet where 80% of calories are coming from ultra processed food

BEHAVIORALDiet containing 20% ultra processed foods

Low ultra processed food diet where 20% of the calories are coming from ultra processed food


Locations(1)

Columbia University Irving Medical Center

New York, New York, United States

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NCT06853288


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