Validation of New Prognostic Biomarkers in Patients With Decompensated Cirrhosis

This study looks for new blood markers (biomarkers) that can predict which patients with advanced liver scarring (decompensated cirrhosis) are most likely to have serious complications or die, helping doctors identify who needs closer monitoring after leaving the hospital. **You may be eligible if:** - You are between 18 and 80 years old - You were hospitalized due to complications of advanced liver disease (such as fluid in the abdomen, confusion, bleeding, or infection) - You have recovered enough to be discharged within 48 hours **You may NOT be eligible if:** - You were admitted for a planned procedure or test (not for liver complications) - You have active cancer (except certain types of liver cancer or skin cancer) - You are HIV-positive (unless on treatment without symptoms) - You have a history of liver transplant or other organ transplant - You have had a procedure to re-route blood around the liver (TIPS or porto-caval shunt) - You have severe kidney, heart, or lung disease - You have severe psychiatric illness or are expected to have poor adherence to the study - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.