RecruitingPhase 4NCT06862739

Glycemic Control With Triple Pathway Approach Through Empagliflozin, Linagliptin and Metformin Combination

Glycemic Control With Triple Pathway Approach Through Empagliflozin-Linagliptin-Metformin


Sponsor

Nabiqasim Industries (Pvt) Ltd

Enrollment

800 participants

Start Date

Oct 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The efficacy and safety of a triple-pill combination therapy for advanced type 2 diabetes care. The study aims to assess the impact of 3 Oral Anti Diabetic (OAD) drugs on metabolic control, patient compliance, weight management, quality of life, diabetic treatment satisfaction and frequency of hypoglycemic events by combining them into a fixed-dose single pill.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria6

  • Patients of any gender
  • Patients aged between 18-80 years
  • Patients having HbA1c 8 % or above
  • Patients diagnosed with type II diabetes (more than at least 06 months)
  • Patients already on at least 02 or more anti-diabetic agents
  • Patients not allergic to empagliflozin, linagliptin, or metformin

Exclusion Criteria11

  • Patients with age less than 18
  • Patients with Type-I diabetes
  • Patients having diabetes for less than 06 months
  • Patients on GLP-1 and GIP
  • Patients who are pregnant or lactating females
  • Patients with decompensated chronic liver disease (DCLD)
  • Patients with eGFR less than 30 ml
  • Patients with end-stage heart failure (NYHA Class 4)
  • Patients who are allergic to empagliflozin, linagliptin, or metformin
  • Patients who are not willing to consent
  • Patients who are unable to give medical history

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Interventions

COMBINATION_PRODUCTEmpagliflozin+Linagliptin+Metformin

Scarcity of local population data on triple drug combination's impact on compliance, efficacy and safety in diabetic patients


Locations(2)

Faisalabad clinics

Faisalabad, Punjab Province, Pakistan

Aap ka Clinic

Lahore, Punjab Province, Pakistan

View Full Details on ClinicalTrials.gov

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NCT06862739


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