RecruitingPhase 4NCT06864026

A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)

A Phase 4, Prospective, Open-Label, Single-Arm Study to Assess the Effectiveness of Tirzepatide After Initiation of Ixekizumab in Adult Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice.

Sponsor

Eli Lilly and Company

Enrollment

200 participants

Start Date

Mar 6, 2025

Study Type

INTERVENTIONAL

Conditions

Psoriatic Arthritis Overweight or Obesity

Summary

The main purpose of this study is to assess the effectiveness of adding tirzepatide to ixekizumab therapy in standard clinical practice in participants with active PsA and obesity or overweight with at least 1 weight-related comorbidity. The study will last up to 12 months.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Tirzepatide for people with overweight or obesity and psoriatic arthritis. The study is currently recruiting participants at 55 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGTirzepatide

Administered SC

Locations(55)

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Avondale

Avondale, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Chandler

Chandler, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Flagstaff

Flagstaff, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Gilbert

Gilbert, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Glendale

Glendale, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Mesa

Mesa, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Phoenix PV

Phoenix, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Sun City

Sun City, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson

Tucson, Arizona, United States

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson Southeast

Tucson, Arizona, United States

Medvin Clinical Research - Apple Valley

Apple Valley, California, United States

Medvin Clinical Research - Covina

Covina, California, United States

Newport Huntington Medical Group

Huntington Beach, California, United States

Purushotham & Akther Kotha MD, Inc

La Mesa, California, United States

Medvin Clinical Research - Riverside

Riverside, California, United States

Rheumatology Center of San Diego

San Diego, California, United States

Providence Saint John's Medical Foundation

Santa Monica, California, United States

Medvin Clinical Research - Temecula

Temecula, California, United States

Medvin Clinical Research - Tujunga

Tujunga, California, United States

Medvin Clinical Research - Whittier

Whittier, California, United States

Vida Clinical Research

Kissimmee, Florida, United States

Life Clinical Trials

Margate, Florida, United States

CZ Rheumatology

Miami Beach, Florida, United States

Vitalia Medical Research

Palm Beach Gardens, Florida, United States

International Center for Research

Tampa, Florida, United States

Atlanta Research Center for Rheumatology

Marietta, Georgia, United States

Satilla Rheumatology & Internal Medicine

Waycross, Georgia, United States

Great Lakes Clinical Trials - Ravenswood

Chicago, Illinois, United States

Greater Chicago Specialty Physicians

Schaumburg, Illinois, United States

Arnold Arthritis & Rheumatology

Skokie, Illinois, United States

Willow Rheumatology and Wellness PLLC

Willowbrook, Illinois, United States

Lake Cumberland Rheumatology

New Albany, Indiana, United States

Accurate Clinical Research, Inc

Lake Charles, Louisiana, United States

Klein & Associates, M.D., P.A.

Cumberland, Maryland, United States

Klein & Associates, M.D., P.A.

Hagerstown, Maryland, United States

Clinical Research Institute of Michigan, LLC

Saint Clair Shores, Michigan, United States

Logan Health Rheumatology

Kalispell, Montana, United States

University of Rochester Medical Center

Rochester, New York, United States

Onsite Clinical Solutions, LLC - Brenner Ave

Salisbury, North Carolina, United States

Paramount Medical Research & Consulting, LLC

Middleburg Heights, Ohio, United States

Essential Medical Research

Tulsa, Oklahoma, United States

West Tennessee Research Institute

Jackson, Tennessee, United States

AARA Clinical Research - Murfreesboro Medical Clinic

Murfreesboro, Tennessee, United States

Precision Comprehensive Clinical Research Solutions - Colleyville

Colleyville, Texas, United States

AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Fort Worth

Fort Worth, Texas, United States

Accurate Clinical Research, Inc

Houston, Texas, United States

Research Physicians Network, LLC

Houston, Texas, United States

AARA Clinical Research - Lone Star Arthritis and Rheumatology Associates - Irving

Irving, Texas, United States

Biopharma Informatic, LLC

Katy, Texas, United States

Advanced Rheumatology of Houston - Woodlands

The Woodlands, Texas, United States

DM Clinical Research - TRA

Tomball, Texas, United States

Seattle Rheumatology Associates PLLC

Seattle, Washington, United States

Arthritis Northwest, PLLC

Spokane Valley, Washington, United States

Reuviva Research Center

Guaynabo, Puerto Rico

CMRC Headlands, LLC

San Juan, Puerto Rico

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT06864026

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