A Single-arm, Phase II Clinical Trial of ASPIRin to prEvent Venous Thromboembolism in Patients With Advanced Germ Cell Tumors Receiving Chemotherapy

This study tests whether low-dose aspirin can prevent dangerous blood clots (venous thromboembolism) in patients with advanced germ cell tumors (like testicular cancer) who are receiving chemotherapy. **You may be eligible if...** - You are between 18 and 70 years old - You have been confirmed to have stage IS, IIA, or higher testicular or germ cell cancer (including primary mediastinal or retroperitoneal types) - You are about to start chemotherapy for this cancer - You are in reasonable general health **You may NOT be eligible if...** - You are already on blood thinners (anticoagulants) for another reason - You have a history of active bleeding or an ulcer - You have a known allergy to aspirin - You have had a blood clot (DVT or PE) before this diagnosis Talk to your doctor to see if this trial is right for you.