Strength-Endurance Circuit Training in Parkinson's Disease
Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.
General University Hospital, Prague
90 participants
Mar 3, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training. \- Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training? Participants will: * undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement, * visit the clinic twice a week for 1-hour training sessions. * selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period
Eligibility
Inclusion Criteria4
- age ≥18 years
- diagnosis of idiopathic Parkinson´s disease
- Hoehn-Yahr Scale ≤ 2,5
- stable dopaminergic medication
Exclusion Criteria9
- age ≥75 years
- Hoehn-Yahr Scale ≥ 2,5
- deep brain stimulation
- presence of freezing
- Camptocormia
- inability to walk without support
- inability to perform study procedures
- limiting co-morbidities
- attendance at training sessions below 70%
Interventions
The intervention for the experimental Strength-Endurance group includes warm-up, three laps of strength and endurance exercises and cool-down. The training program lasts 3 months and includes two 1-hour training sessions per week, for a total of 24 sessions.
The intervention for the control Endurance training group includes warm-up, three laps of endurance exercises and cool-down. The training program lasts 3 months and includes two 1-hour training sessions per week, for a total of 24 sessions.
Locations(1)
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NCT06893055