RecruitingNot ApplicableNCT06893055

Strength-Endurance Circuit Training in Parkinson's Disease

Strength-Endurance Circuit Training in Parkinson's Disease: Effects on Disease Severity, Physical Performance, Blood Biomarkers and Quality of Life.

Sponsor

General University Hospital, Prague

Enrollment

90 participants

Start Date

Mar 3, 2025

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease, Idiopathic

Summary

The goal of this clinical trial is to determine whether adding strength training to aerobic training has a comparable or greater effect on the clinical status of Parkinson's disease patients than a standalone aerobic training. \- Does combined strength-endurance circuit training provide added benefits to physical performance, disease severity, blood biomarkers, and quality of life in PD patients compared to standalone aerobic training? Participants will: * undergo outcome measurements before and after the 12-week intervention and a 3-month follow-up measurement, * visit the clinic twice a week for 1-hour training sessions. * selected patients will be given a smartwatch with a pedometer that will count their average number of steps before, during and after the training period

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a specific circuit training program that combines strength and endurance exercises can improve physical fitness, balance, and quality of life in people with Parkinson's disease in the earlier stages of the condition. **You may be eligible if...** - You are 18 years or older (but under 75) - You have been diagnosed with idiopathic Parkinson's disease (the most common type) - Your disease is at stage 2.5 or below on the Hoehn-Yahr scale (mild to moderate) - Your medication regimen has been stable **You may NOT be eligible if...** - You are 75 or older - Your Parkinson's is at stage 2.5 or above on the Hoehn-Yahr scale - You have had deep brain stimulation surgery - You experience freezing of gait (sudden inability to walk) - You need support to walk - You cannot commit to attending at least 70% of training sessions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERStrength-Endurance Training

The intervention for the experimental Strength-Endurance group includes warm-up, three laps of strength and endurance exercises and cool-down. The training program lasts 3 months and includes two 1-hour training sessions per week, for a total of 24 sessions.

OTHEREndurance Training

The intervention for the control Endurance training group includes warm-up, three laps of endurance exercises and cool-down. The training program lasts 3 months and includes two 1-hour training sessions per week, for a total of 24 sessions.

Locations(1)

Department of Neurology and Centre of Clinical Neuroscience First Faculty of Medicine, Charles University and General University Hospital in Prague

Prague, Prague, Czechia

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NCT06893055

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