Tamoxifen for Advanced Solid Pseudopapillary Tumor of the Pancreas

This study is testing tamoxifen — a hormone-blocking drug commonly used in breast cancer — for people with advanced solid pseudopapillary tumor of the pancreas (SPTP), a rare type of pancreatic tumor that often has hormone receptors. **You may be eligible if...** - You are between 14 and 80 years old - You have a confirmed diagnosis of SPTP that has hormone receptors (ER/PR positive) - Your cancer has spread, cannot be surgically removed, or has come back after prior treatment - You have at least one measurable tumor - Your overall health and organ function are adequate **You may NOT be eligible if...** - Your tumor is not confirmed as SPTP - You have active inflammation of the pancreas or gastrointestinal tract - You are pregnant or breastfeeding - You have severe organ dysfunction affecting the heart, kidneys, liver, or lungs Talk to your doctor to see if this trial is right for you.