RecruitingNot ApplicableNCT06917131

Royal Jelly as a Strategy to Modulate Inflammation and Oxidative Stress in Patients With Systemic Arterial Hypertension


Sponsor

Universidade Federal Fluminense

Enrollment

34 participants

Start Date

Sep 18, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The study aims to evaluate the effect of the royal jelly on inflammation and oxidative stress in participants with systemic arterial hypertension. A longitudinal double-blind randomized clinical trial will be carried out, involving hypertensive participants for two months.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether royal jelly — a natural substance produced by bees — can help reduce inflammation and oxidative stress (cellular damage) in patients with high blood pressure (hypertension) who are already taking antihypertensive medications. **You may be eligible if...** - You are a patient being treated for high blood pressure at HUAP Medical Clinic (Brazil) - You have been on 1 to 3 blood pressure medications for more than 6 months - Your medication doses have been stable for at least 3 months - You are not taking any supplements that might interact with the study **You may NOT be eligible if...** - You have autoimmune disease, diabetes, kidney disease, liver disease, cancer, or AIDS - You are pregnant - You are taking antibiotics, catabolic drugs, or antioxidant supplements - You regularly consume royal jelly - You are allergic to bee products or cornstarch - You have had a heart attack or stroke in the last 6 months - You have stage 2 or 3 hypertension Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTRoyal Jelly

Participants will receive 2 capsules per day, providing the dosage of 300mg of royal jelly for 2 months (8 weeks).

DIETARY_SUPPLEMENTPlacebo

The placebo group will receive 2 capsules per day (containing microcrystalline cellulose and magnesium stearate in colored gelatin capsules capable of masking the appearance of the internal content), at the same time for 2 months.


Locations(1)

Denise Mafra

Rio de Janeiro, Brazil

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NCT06917131


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