Effect of Malnutrition on Liver and Spleen Stiffness in Children
Impact of Malnutrition on Liver and Spleen Stiffness in Children Evaluated by Shear Wave Elastography
Mehmet Akif AĞIR
300 participants
Apr 10, 2025
OBSERVATIONAL
Conditions
Summary
This prospective observational study aims to evaluate the effect of malnutrition on liver and spleen stiffness in children using shear wave elastography. Two groups of participants will be enrolled: children diagnosed with malnutrition and age-matched healthy controls. Organ stiffness measurements will be compared between the two groups to assess the impact of malnutrition on liver and spleen tissue properties.
Eligibility
Inclusion Criteria3
- Children aged 6 to 18 years.
- Diagnosis of malnutrition based on World Health Organization (WHO) criteria (for malnutrition group).
- Healthy children without any chronic illness (for control group).
Exclusion Criteria3
- Children with chronic diseases (e.g., liver disease, diabetes, immunocompromised conditions).
- Children who have previously undergone liver or spleen surgery.
- Children with inability to cooperate during elastography measurement.
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Interventions
Shear wave elastography will be used to measure liver and spleen stiffness in all participants. The procedure will be performed using standard ultrasound-based elastography protocols by a pediatric radiologist.
Locations(1)
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NCT06932445