RecruitingNot ApplicableNCT06936397

Cognitive Remediation Therapy for Schizophrenia: Effects on EEG and Emotional Regulation

A Randomized Controlled EEG-GSR Study on the Effects of Cognitive Remediation Therapy on Neurophysiological and Emotional Regulation Markers in Schizophrenia


Sponsor

Beykoz University

Enrollment

60 participants

Start Date

Mar 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to determine whether Cognitive Remediation Therapy (CRT) can improve attention, memory, and emotional regulation in people with schizophrenia. CRT is a structured program that includes exercises to strengthen cognitive skills such as problem-solving, working memory, and emotion regulation. The study will recruit 60 participants: 30 individuals with schizophrenia and 30 healthy individuals of similar age and gender. Those with schizophrenia will be randomly assigned to either receive CRT or be placed on a waitlist without therapy. All participants will undergo non-invasive brain activity (EEG) and emotional response (GSR) recordings before and after the therapy. The study's main question is: Does participating in a 12-week CRT program improve brain-based markers of attention and emotional regulation in people with schizophrenia? Additional tests, such as memory and emotion recognition tasks and self-report questionnaires, will help assess changes in thinking skills and emotional well-being. The study may help better understand how CRT affects both brain function and quality of life in schizophrenia.


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This study is testing cognitive remediation therapy (CRT) for people with schizophrenia. CRT is a type of brain training that helps improve thinking skills like memory, attention, and problem-solving that are often affected by schizophrenia. Researchers want to see how it affects brain activity and everyday functioning. **You may be eligible if...** - You have been diagnosed with schizophrenia or a related psychotic disorder - You are an adult (18 or older) in a stable phase of your illness (not in acute crisis) - You have some cognitive difficulties affecting your daily life - You are willing to participate in multiple therapy sessions and assessments **You may NOT be eligible if...** - You are currently experiencing an acute psychotic episode - You have significant neurological conditions affecting thinking (such as brain injury or dementia) - You have severe substance use disorders - You are unable to commit to the full program of sessions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive Remediation Therapy

CRT is a structured behavioral intervention consisting of weekly 60-minute sessions for 12 weeks. The therapy includes tasks to enhance cognitive skills such as attention, memory, executive function, and emotional regulation using computer-based training and therapist-guided exercises.


Locations(1)

Beykoz University

Istanbul, Turkey (Türkiye)

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NCT06936397


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