RecruitingPhase 4NCT06953440

The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema

The Effect of Dexamethasone Submucosal Injection After Third Molar Surgery on Trismus and Edema


Sponsor

King Abdulaziz University

Enrollment

66 participants

Start Date

Feb 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction. The main question it aims to answer is: Does dexamethasone submucosal injection have a positive impact on trismus and edema after third molar surgery compared to conventional postoperative prescription? Participants will: * Be administered with dexamethasone submucosal injection or a placebo after the surgery. * Visit the clinic three times the week after the extraction for follow-up.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria3

  • Patients with impacted lower third molars requiring surgical extraction.
  • Adults over the age of 18 years old.
  • American Society of Anaesthesiologists (ASA) 1, and ASA 2

Exclusion Criteria6

  • Patients with preoperative intraoral or extraoral swelling.
  • Patients requiring simple extraction (Class I group A according to Pell and ---Gregory classification).
  • Patients with uncontrolled systemic disease such as uncontrolled diabetic - patients.
  • Patients who are allergic to corticosteroids.
  • Patients who are contraindicated to use corticosteroids such as uncontrolled diabetic patients, and osteoporotic patients.
  • Patients who require extraction of additional teeth at the same visit.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGDexamethasone Sodium Phosphate Injection

Patients will receive 4 milligrams of dexamethasone submucosal injection next to the extraction site.

OTHERNormal Saline (Placebo)

Patients will receive 4 milligrams of normal saline solution next to the extraction site.


Locations(1)

King Abdulaziz University, Faculty of Dentistry

Jeddah, Mecca Region, Saudi Arabia

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06953440


Related Trials