RecruitingNot ApplicableNCT07180498

Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction

The Evaluation of the Effects of Chlorhexidine and Tea Tree Oil Mouthwash on Postoperative Complications and Periodontal Healing After the Extraction of Impacted Third Molars


Sponsor

Harran University

Enrollment

54 participants

Start Date

Apr 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this clinical study is to compare the effects of mouthwashes containing Chlorhexidine and tea tree oil on edema, pain, and trismus after the extraction of impacted third molars. Additionally, the effects on periodontal health will be examined by comparing the gum healing processes of patients using both mouthwashes.The main questions it aims to answer are: 1. Tea tree oil, said to have anti-inflammatory and antibacterial effects, could be an alternative to chlorhexidine in reducing postoperative complications after impacted tooth extraction. 2. Does tea tree oil, which has antimicrobial effects, have as positive an impact on periodontal health as chlorhexidine?Researchers will compare tea tree oil to chlorhexidine (routinely prescribed after the extraction of an impacted wisdom tooth) to see if tea tree oil works to decrease postoperative complications. Participants will: For 7 days after the operation, they will gargle with chlorhexidine mouthwash or mouthwash containing tea tree oil 3 times a day. They will come to the clinic for check-ups and measurements on the 2nd and 7th days after the operation. They will record their pain levels and the number of painkillers they take daily.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria4

  • Individuals undergoing extraction of Class 2, Class B mandibular third molars impacted in the lower jaw (Pell \& Gregory).
  • Individuals aged 18-65.
  • Individuals must be in stable general health (e.g., free of serious cardiovascular or kidney disease).
  • Individuals willing to use tea tree extract or other treatments.

Exclusion Criteria6

  • Individuals with a known allergy or hypersensitivity to tea tree extract.
  • Individuals with serious illnesses such as heart failure or kidney disease. Patients with bleeding disorders.
  • Individuals during pregnancy and breastfeeding.
  • Individuals taking medications that may interact with tea tree extract (e.g., blood thinners or antihypertensives)
  • Individuals previously treated for edema.
  • Individuals with chronic edema.

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Interventions

DRUGChlorhexidine Gluconate 0.12% Mouthwash

Participants will be prescribed to gargle with chlorhexidine, which is the routine recommendation after brushing their teeth 3 times a day for 7 days after the impacted tooth extraction.

DRUGTea Tree Oil mouthwash

Participants will be prescribed to gargle with tea tree oil-containing water after brushing their teeth three times a day for 7 days following the extraction of an impacted tooth.


Locations(1)

Harran University, Faculty of Dentistry

Sanliurfa, Turkey (Türkiye)

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NCT07180498


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