Trismus Clinical Trials

12 recruiting

Trismus Trials at a Glance

10 actively recruiting trials for trismus are listed on ClinicalTrialsFinder across 6 cities in 8 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Edmonton, Istanbul, and Jeddah. Lead sponsors running trismus studies include Chris O'Brien Lifehouse, Harran University, and Azienda Ospedaliera di Perugia.

Browse trismus trials by phase

Treatments under study

About Trismus Clinical Trials

Looking for clinical trials for Trismus? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Trismus trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Trismus clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 110 of 10 trials

Recruiting
Not Applicable

Feasibility of Prospective Surveillance and Early Physical Therapy for Trismus

Head and Neck CancerTrismus
University of Alberta30 enrolled1 locationNCT06531083
Recruiting
Not Applicable

Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery

Postoperative PainTrismusFacial Swelling
Oman Medical Speciality Board100 enrolled1 locationNCT07244029
Recruiting
Not Applicable

Evaluation of the Effect of Tea Tree and Chlorhexidine Mouthwashes on Healing After Third Molar Extraction

Postoperative PainPostoperative ComplicationsTrismus+1 more
Harran University54 enrolled1 locationNCT07180498
Recruiting
Not Applicable

Hilotherapy vs. Kinesio Taping in Orthognathic Surgery Recovery

Postoperative PainTrismusPostoperative Edema+1 more
Medipol University36 enrolled1 locationNCT07006610
Recruiting
Not Applicable

Manual Therapy on Oral Opening, Swallow Function and Upper Quarter Mobility on Head and Neck Cancer Survivors

Head and Neck CancerTrismusDysfunction
Universidad de La Frontera70 enrolled2 locationsNCT06148077
Recruiting
Phase 4

The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema

TrismusSwelling/ Edema
King Abdulaziz University66 enrolled1 locationNCT06953440
Recruiting

Assessing the effectiveness of Hospital-Based Manufactured Medical Device Restorabite for treatment of Trismus in adults after head and neck cancer surgery (Cohort 2)

Head and Neck CancerTrismus
Chris O'Brien Lifehouse280 enrolled6 locationsACTRN12625000200482
Recruiting
Phase 4

Efficacy of Botox Injection of the Masticatory Muscles in Head &Neck Cancer Patients with Trismus After Radiotherapy

Head and Neck CancerTrismusRadiation Therapy Recipient+1 more
National Taiwan University Hospital120 enrolled1 locationNCT06734598
Recruiting
Not Applicable

Effects of the Application of a Hyper-oxygenated Gel After Oral Surgery

PainTrismusEdema Face+2 more
Azienda Ospedaliera di Perugia72 enrolled1 locationNCT06458478
Recruiting

Assessing the effectiveness of Hospital-Based Manufactured Medical Device Restorabite for treatment of Trismus in adults after head and neck cancer surgery

Head and Neck CancerTrismus
Chris O'Brien Lifehouse150 enrolled2 locationsACTRN12621000585820