The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study
The Effect of Serum Calcium Levels on Postoperative Pain in Patients Undergoing Abdominal Surgery: A Prospective Observational Study
The Second Affiliated Hospital of Chongqing Medical University
350 participants
Jul 1, 2025
OBSERVATIONAL
Conditions
Summary
This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.
Eligibility
Inclusion Criteria4
- Aged 18-70 years old
- American Society of Anesthesiologists Classification I-III
- Patients undergoing elective abdominal surgery under general anesthesia
- Patients participate voluntarily and sign an informed consent form
Exclusion Criteria6
- Patients with a history of severe disease
- Patients with chronic preoperative pain and/or long-term analgesic use
- Patients with hearing disorders or verbal communication difficulties
- Patients with psychiatric disorders or cognitive dysfunction
- Patients requiring mechanical ventilation or ICU admission after surgery
- Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason
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Interventions
Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.
Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.
Locations(1)
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NCT06957158