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RecruitingNot ApplicableNCT06964581

Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis

Cognitive Rehabilitation of Deficits in Patients With Multiple Sclerosis: Proposal for an Integrated Cognitive Treatment in a Telematic Format

Sponsor

Universita di Verona

Enrollment

60 participants

Start Date

Feb 8, 2023

Study Type

INTERVENTIONAL

Conditions

Cognitive DisordersMultiple SclerosisTelerehabilitationNeurorehabilitation

Summary

Non-Inferiority Study, Post-Market Clinical Investigation with a Device, Single-Blind Randomized Controlled Trial in a Cohort of Patients Diagnosed with Multiple Sclerosis (MS). The aim of the study is to assess whether a computer-based cognitive treatment delivered via telerehabilitation produces effects from T0 to T1 that are not inferior to those of an in-person treatment on sustained attention in a cohort of patients with MS. The secondary objective is to evaluate the effects of telerehabilitation compared to the same treatment delivered in person on attentional shifting, memory, executive functions, and daily functioning (including cognitive fatigue, quality of life, and mood) in patients with MS.

Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a digital cognitive rehabilitation program designed to help people with multiple sclerosis (MS) who are experiencing problems with memory, attention, or thinking clearly. **You may be eligible if...** - You have a confirmed diagnosis of relapsing-remitting, primary progressive, or secondary progressive MS for at least 3–6 months - You are between 18 and 65 years old - You have mild to moderate disability from MS - You are experiencing one or more cognitive issues such as memory or attention problems (confirmed by a cognitive screening test) **You may NOT be eligible if...** - You have severe physical disability that prevents participation - You have no cognitive difficulties - You have a condition that would prevent using digital tools or completing assessments Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive treatment delivered via telerehabilitation.

Three hours of cognitive rehabilitation per week, carried out independently and remotely using a computerized device, which is pre-programmed according to the patient's specific needs.

BEHAVIORALIn-person cognitive treatment.

Three hours of in-person cognitive rehabilitation per week using a computerized device. The participant will perform cognitive exercises on the computerized device in the presence of the therapist, who will activate the device (using credentials specifically created for them) and select the appropriate activity to administer at each session.

Locations(1)

Azienda Ospedaliera Universitaria Integrata Verona - UOC di Neuroriabilitazione

Verona, verona, Italy

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NCT06964581

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