RecruitingNCT06978322

Comparative Study Between Immediate Surgery Versus Neoadjuvant Chemotherapy for Management of Resectable Pancreatic Cancer


Sponsor

Minia University

Enrollment

30 participants

Start Date

Feb 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This trial aimed to determine whether neoadjuvant chemoradiotherapy improves overall survival compared with upfront surgery, both followed by adjuvant chemotherapy in patients with resectable and borderline resectable pancreatic cancer.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two approaches for treating resectable (surgically removable) pancreatic cancer: going straight to surgery versus first giving chemotherapy to shrink the tumor before surgery. The goal is to find out which approach leads to better outcomes. **You may be eligible if...** - You have been diagnosed with pancreatic cancer confirmed by biopsy - Your cancer has been assessed as surgically removable (the tumor does not touch or wrap around major blood vessels) - You have had appropriate CT imaging to map the tumor and blood vessels **You may NOT be eligible if...** - Your tumor is borderline resectable or considered locally advanced (too close to blood vessels) - Your cancer is located in the tail of the pancreas - Your cancer has spread to other parts of the body - You are not medically fit for surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREImmediate surgery

Patients will undergo upfront surgery, then adjuvant chemotherapy.

PROCEDURENeoadjuvant chemotherapy

Patients will undergo neoadjuvant chemotherapy, then surgery.


Locations(1)

Minia University

Minya, Egypt

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NCT06978322


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