Hypofractionated Radiotherapy With Concomitant Tumor Bed Boost for Breast Cancer

This study is comparing a newer approach to radiation therapy for early-stage breast cancer called hypofractionated radiotherapy with a simultaneous tumor bed boost (delivering higher radiation doses in fewer sessions, with extra dose to the original tumor site) against standard radiotherapy techniques. Breast-conserving surgery followed by radiation is a common treatment, and this study aims to find the most effective radiation schedule. **You may be eligible if...** - You are a woman aged 20 or older - You have been diagnosed with early-stage breast cancer (T1 or T2, N0 or N1) or ductal carcinoma in situ (DCIS — a non-invasive form) - You have undergone breast-conserving surgery (lumpectomy) - You are in generally good health with adequate kidney and liver function **You may NOT be eligible if...** - You are pregnant - You have previously received radiation to the chest area and need re-irradiation Talk to your doctor to see if this trial is right for you.