RecruitingNCT06984250

Hypofractionated Radiotherapy With Concomitant Tumor Bed Boost for Breast Cancer

Hybrid Techniques Combining Hypofractionated Whole Breast Radiotherapy With Concomitant Tumor Bed Boost in Patients With Breast Cancer


Sponsor

National Taiwan University Hospital

Enrollment

315 participants

Start Date

Feb 6, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Hypofractionated breast radiotherapy with concomitant tumor bed boost for early breast cancer or ductal breast carcinoma in situ after partial mastectomy


Eligibility

Sex: FEMALEMin Age: 20 YearsMax Age: 85 Years

Inclusion Criteria6

  • Female patients with histologically confirmed early-stage breast cancer (T1-2 and N0-1) or ductal carcinoma in situ (DCIS).
  • Patients undergoing breast-conserving surgery
  • Age ≥ 20 years
  • Karnofsky Performance Status (KPS) ≥70%
  • Life expectancy ≥ 5 years
  • Adequate renal and hepatic function

Exclusion Criteria2

  • Pregnant patients
  • Patients requiring re-irradiation of the thoracic region

Interventions

RADIATIONHypofractionated Radiation Therapy

Hypofractionated breast radiotherapy (HFRT) with hybrid techniques combining field-in-field intensity-modulated RT (FIF-IMRT) to the whole breast with inverse-IMRT for concomitant boost


Locations(2)

National Taiwan University Hospital

Taipei, Taiwan, Taiwan

National Taiwan University Hospital Yunlin Branch

Taipei, Taiwan

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NCT06984250


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