RecruitingNot ApplicableNCT06987799

Community-based Approach to Lowering Stress Through Mindfulness

Addressing Depression for African American Adults With Hypertension: Applying Community-Engaged Implementation Science


Sponsor

Northwestern University

Enrollment

60 participants

Start Date

Sep 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to test a culturally adapted mindfulness-based stress reduction intervention in a community setting for African American adults with high blood pressure (hypertension) and depression. The main questions it aims to answer are: * Does participation in a culturally adapted mindfulness-based intervention improve depressive symptoms? * Does participation in a culturally adapted mindfulness-based intervention improve blood pressure control? * Is the intervention acceptable, appropriate, and feasible as delivered in a community setting? Participants will: * Participate in an 8-week group-based mindfulness intervention (CALM-Chicago). During intervention sessions, participants will learn about mindfulness and stress management and complete mindfulness-based activities, such as guided deep breathing and meditation. * Complete surveys online * Have their blood pressure measured with a non-invasive blood pressure cuff * Attend 1 focus group (optional)


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • ≥18 years old
  • Lives, works, or spends much of their time in the South Side of Chicago neighborhood
  • Self-reports diagnosis of hypertension or high blood pressure by a clinician
  • Endorses elevated depressive symptoms as Patient Health Questionnaire (PHQ)-9 scores ≥10
  • Not taking antidepressant medication or stable on antidepressant medication for ≥6 months as self-reported

Exclusion Criteria4

  • <18 years old
  • Severe mental illness (e.g., bipolar disorder, psychosis)
  • Current suicidal ideation (PHQ-9 item 9) or recent (past 6 months) suicide attempt
  • Unable to provide informed consent or complete study activities in English

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Interventions

BEHAVIORALMindfulness-Based Stress Reduction (MBSR; CALM-Chicago Study)

This clinical trial will evaluate the effectiveness of the culturally adapted intervention, CALM-Chicago, in a community setting. CALM-Chicago has been previously used in a clinical setting.


Locations(1)

The Salvation Army Ray and Joan Kroc Corps Community Center Chicago

Chicago, Illinois, United States

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NCT06987799


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