Post Prandial Individual Responses to Different Foods
Quantifying Differential Individual Responses to OGTT, Starchy Foods, and Mitigators and Its Association With Metabolic Subphenotypes
Stanford University
100 participants
Oct 1, 2025
INTERVENTIONAL
Conditions
Summary
This study aims to understand why people respond differently to the same foods, especially when it comes to changes in blood sugar after eating. A continuous glucose monitors (CGMs) will be used to observe how individuals respond to specific meals and drinks (e.g., Oral Glucose Tolerance Test, OGTT). By studying these patterns, the investigators hope to identify different types of metabolism and see if certain foods or food ingredients (like fiber, amino acids, or vinegar) can help control blood sugar better for specific groups. This research will help lay the groundwork for personalized dietary advice based on a person's unique biology.
Eligibility
Inclusion Criteria4
- BMI (body mass index) \>19 kg/m2 but \< 45 kg/m2
- HbA1c \< or equal to 7.0% while not on antihyperglycemic medications
- Be willing to provide written informed consent for all study procedures.
- Able to commute to Stanford campus for on-site visits
Exclusion Criteria12
- recent (\<6mos) CVD (cardiovascular disease) event
- active malignancy
- kidney/liver disease
- pregnancy/lactation
- chronic inflammatory disease
- eating disorder
- bariatric surgery
- history of acute pancreatitis
- current use of antihyperglycemic, diabetogenic, or weight loss medications
- heavy alcohol use
- physical activity \>2 hours/day
- inability to come to Stanford CTRU (Clinical and Translational Research Unit) for metabolic testing
Interventions
A variety of foods, supplements, and short prescriptive exercise will be tested to see which one helps mitigate the rise is postprandial glucose after eating carbohydrate containing foods.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06989164