RecruitingNCT06994689

Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD

Clinimetric Properties Assessment of Quadriceps Muscle Mass and Stiffness Using Perimetry and ShearWave Elastography in Patients With COPD : a Prospective Observational Study

Sponsor

Groupe Hospitalier du Havre

Enrollment

30 participants

Start Date

May 30, 2025

Study Type

OBSERVATIONAL

Conditions

COPD Quadriceps Muscle Atrophy

Summary

A large amount of patients with COPD suffer from muscle dysfunction characterized by losses of muscle mass and strength. Studies have shown an association between a loss of quadriceps muscle mass and premature death. This study aims to investigate the clinimetric properties of a simple quadriceps perimetry and ShearWave elastography to improve the monitoring of skeletal muscle function in patients with COPD.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

COPD patients
Adults (\>18 years old)
Patients starting a pulmonary rehabilitation (PR) programme

Exclusion Criteria5

Patients included in other research protocol
Minors or under guardianship
Pregnancy
Patients with lower limb amputation or history of neuromuscular disease
Cardiovascular contradications for PR

Interventions

DIAGNOSTIC_TESTPerimetry and ShearWave measurement of the quadriceps muscle before and after a pulmonary rehabilitation (PR) programme

Patients will undergo a pulmonary rehabilitation (PR) programme. On day 1, perimetry and ShearWave measurements of the quadriceps muscle will be provided. Supplementary assessments of quadriceps thickness, quadriceps strength with a handheld dynamometry, lean body mass (bioelectrical impedance), constant work-rate endurance test and HAD questionnaire will also be provided on day 1. The same measurements and questionnaire will be provided on the last day of the patient in the PR programme.