RecruitingNCT06994689

Clinimetric Properties of Muscle Mass and Stiffness Measurements of the Quadriceps in Patients With COPD

Clinimetric Properties Assessment of Quadriceps Muscle Mass and Stiffness Using Perimetry and ShearWave Elastography in Patients With COPD : a Prospective Observational Study


Sponsor

Groupe Hospitalier du Havre

Enrollment

30 participants

Start Date

May 30, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

A large amount of patients with COPD suffer from muscle dysfunction characterized by losses of muscle mass and strength. Studies have shown an association between a loss of quadriceps muscle mass and premature death. This study aims to investigate the clinimetric properties of a simple quadriceps perimetry and ShearWave elastography to improve the monitoring of skeletal muscle function in patients with COPD.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is measuring muscle mass and stiffness in the thigh muscles (quadriceps) of patients with chronic obstructive pulmonary disease (COPD) who are starting a pulmonary rehabilitation program. COPD causes the lungs to work poorly, and over time many patients lose significant muscle strength and mass — which affects their ability to exercise and recover. Researchers want to know how reliable these measurements are and whether they improve after the rehabilitation program, which could help doctors better track patient progress. **You may be eligible if...** - You have been diagnosed with COPD - You are an adult over 18 years old - You are starting a pulmonary rehabilitation program **You may NOT be eligible if...** - You are already enrolled in another research study - You are a minor or under legal guardianship - You are pregnant - You have had a leg amputation or have a neuromuscular disease - You have heart conditions that make pulmonary rehabilitation medically unsafe Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTPerimetry and ShearWave measurement of the quadriceps muscle before and after a pulmonary rehabilitation (PR) programme

Patients will undergo a pulmonary rehabilitation (PR) programme. On day 1, perimetry and ShearWave measurements of the quadriceps muscle will be provided. Supplementary assessments of quadriceps thickness, quadriceps strength with a handheld dynamometry, lean body mass (bioelectrical impedance), constant work-rate endurance test and HAD questionnaire will also be provided on day 1. The same measurements and questionnaire will be provided on the last day of the patient in the PR programme.


Locations(1)

Groupe Hospitalier du Havre

Le Havre, France

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NCT06994689


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