RecruitingNCT07003672
Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation
Sponsor
National Taiwan University Hospital
Enrollment
120 participants
Start Date
Jan 16, 2025
Study Type
OBSERVATIONAL
Conditions
Summary
This project focuses on the analysis of the correlation between transpulmonary driving pressure and uneven lung ventilation and regional lung compliance in patients using prolonged mechanical ventilation (PMV), in order to understand the clinical occurrence of failure of the final spontaneous breathing test and inability to breathe. Respiratory physiology impairments in patients successfully discharged from respirators.
Eligibility
Min Age: 20 Years
Inclusion Criteria3
- Post-tracheostomy patients who are transferred to the subacute respiratory care ward of National Taiwan University Hospital must use respirators for at least 14 days;
- Be at least 20 years old;
- The oxygen concentration required when using the respirator does not exceed 50%
Exclusion Criteria5
- The vital signs are unstable or require continuous use of vasopressors;
- Pregnancy;
- Chronic obstructive pulmonary disease or asthma;
- Those who have contraindications to the placement of esophageal pressure balloons, such as abnormal blood coagulation, esophageal varices, and those who have undergone esophageal or gastric surgery in the past six months;
- Those who have contraindications to the use of electrical impedance tomography, such as heart rhythm regulators.
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07003672
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