Weaning Failure Clinical Trials

12 recruiting

Weaning Failure Trials at a Glance

16 actively recruiting trials for weaning failure are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Istanbul, Beijing, and Buenos Aires. Lead sponsors running weaning failure studies include Kanuni Sultan Suleyman Training and Research Hospital, Centre Hospitalier Régional d'Orléans, and Benha University.

Browse weaning failure trials by phase

Treatments under study

About Weaning Failure Clinical Trials

Looking for clinical trials for Weaning Failure? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Weaning Failure trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Weaning Failure clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting
Not Applicable

Improving Our Understanding of Respiratory Muscle Training to Facilitate Weaning From Mechanical Ventilation in the ICU

Weaning Failure
KU Leuven90 enrolled1 locationNCT04658498
Recruiting
Not Applicable

Speckle Tracking Echocardiography for the Prediction of Weaning Failure

Weaning Failure of Mechanical Ventilation
Assistance Publique Hopitaux De Marseille110 enrolled1 locationNCT03657524
Recruiting
Not Applicable

Evaluation of heepSync, a Novel Algorithm for Transcutaneous Electrical Stimulation of Respiratory Muscles in Mechanically Ventilated Patients.

Weaning FailureVentilator-induced Diaphragm DysfunctionVIDD
Tesai Care SL20 enrolled3 locationsNCT07363902
Recruiting
Phase 4

Shorter Weaning From Invasive Ventilation With Levosimendan

Mechanical VentilationWeaning Failure
Radboud University Medical Center250 enrolled8 locationsNCT07105202
Recruiting

Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit

Mechanical VentilationCritical IllnessIntensive Care Units (ICUs)+3 more
Leiden University Medical Center60 enrolled1 locationNCT07109570
Recruiting

Evaluation of Left Ventricular Function to Predict Weaning Success in the Intensive Care Unit

Weaning Failure of Mechanical Ventilation
Kanuni Sultan Suleyman Training and Research Hospital50 enrolled1 locationNCT07075926
Recruiting

Evaluation of Right Ventricular Function to Predict Weaning Success in the Intensive Care Unit

Weaning Failure of Mechanical Ventilation
Kanuni Sultan Suleyman Training and Research Hospital60 enrolled1 locationNCT07073976
Recruiting

Effect of Hypophosphatemia on Neuro-excursion Efficiency During Mechanical Ventilator Weaning

HypophosphatemiaMechanical VentilationWeaning Failure
Peking Union Medical College70 enrolled1 locationNCT06754670
Recruiting

Role of Regional Lung Compliance and Dynamic Transpulmonary Driving Pressure in the Liberation Difficulty in Tracheostomized Patients Receiving Prolonged Mechanical Ventilation

Weaning Failure
National Taiwan University Hospital120 enrolled1 locationNCT07003672
Recruiting

PREdicting Failure of Non-inVasIve Ventilatory Support Using Non-invaSIve mONitoring in Non-intubated Patients With Acute Hypoxemic Respiratory Failure or Post-extubation Failure. The PREVISION Study

RespiratoryVentilatory FailureHypoxemic Respiratory Failure+1 more
Unity Health Toronto80 enrolled1 locationNCT06716463
Recruiting
Not Applicable

Ultrasound Evaluation of Cardiac Function During Spontaneous Breathing Trials

Weaning Invasive Mechanical VentilationWeaning-induced Pulmonary EdemaWeaning Failure of Mechanical Ventilation+2 more
Centre Hospitalier Régional d'Orléans24 enrolled1 locationNCT06923267
Recruiting

Ventilatory Settings and Monitoring Variables Associated With Weaning Failure in Critically Ill Patients

Mechanical VentilationWeaning Failure of Mechanical VentilationWeaning Failure+1 more
Hospital Italiano de Buenos Aires1,077 enrolled1 locationNCT06683781
Recruiting

Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA

Respiratory FailureWeaning Failure
Fondazione Policlinico Universitario Agostino Gemelli IRCCS20 enrolled1 locationNCT05990348
Recruiting

Predictive Value of Airway Occlusion Pressure, Maximal Inspiratory Pressure and Their Ratio for Successful Extubation in Patients With Traumatic Brain Injury

Weaning Failure
Benha University60 enrolled1 locationNCT06627686
Recruiting

Extremes of Respiratory Effort in Weaning Failure From Mechanical Ventilation: a Prospective Observational Study

Mechanical Ventilation Pressure HighWeaning Failure
Universidade Federal do Rio de Janeiro1 enrolled1 locationNCT06464224
Recruiting

Exploration of Mechanisms for Weaning Failure

Weaning FailureCentral Respiratory DepressionDiaphragm Injury+1 more
The First Affiliated Hospital of Guangzhou Medical University30 enrolled1 locationNCT06424314