Surface Electrical Myography, Oxygen Consumption, Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit
Surface Electrical Myography, Oxygen Consumption (VO2), Effort, and Weaning in the Mechanically Ventilated Patient in the Intensive Care Unit (ICU): SERA-Effort Study
Leiden University Medical Center
60 participants
Jul 8, 2025
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to measure effort using esophageal pressure measurements, oxygen consumption and diaphragm activity in mechanically ventilated Intensive Care Unit patients during a Spontaneous Breathing Trial. The main question aims to answer whether the sEMG signal derived from the SERA device, effort parameters and oxygen consumption have an association with weaning failure. Participants will be measured while performing a spontaneous breathing trial.
Eligibility
Inclusion Criteria3
- years of age or older
- Esophageal catheter in situ (standard of care)
- Eligible for an SBT in the near future according to the LUMC SBT protocol currently valid
Exclusion Criteria4
- Severe cardiac failure NYHA class IV without mechanical support (LVAD or Impella)
- COPD Gold IV
- Pregnancy
- Patients with ECMO
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07109570