RecruitingNot ApplicableNCT07004634

Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE)

Comparison of the Application Effects of Different Drainage Modes in the Perioperative Period of Minimally Invasive Three-Field Radical Esophagectomy for Esophageal Cancer


Sponsor

Ruijin Hospital

Enrollment

75 participants

Start Date

Apr 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing different methods of draining fluid from the chest cavity after minimally invasive esophageal cancer surgery (esophagectomy). The goal is to determine which drainage approach leads to better recovery and less pain. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with esophageal cancer that requires a three-incision esophagectomy (surgery with openings at the neck, chest, and abdomen) - Your overall physical condition is rated as ASA class I, II, or III (broadly healthy to having controlled medical conditions) **You may NOT be eligible if...** - You have a history of chronic pain or long-term use of pain medications before surgery - You have severe heart or lung problems (e.g., FEV1 < 50%) - You have a bleeding disorder or are having a repeat surgery - During surgery, extensive scar tissue is found, or nearby organs need to be removed Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREChest mediastinal tube

Transthoracic mediastinal drainage was performed for postoperative management of the patient.

PROCEDUREAbdominal mediastinal tube

Transperitoneal mediastinal drainage was performed for postoperative management of the patient.

PROCEDUREChest tube + chest mediastinal tube

Chest tube insertion combined with transthoracic mediastinal drainage was performed for postoperative management of the patient.


Locations(1)

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

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NCT07004634


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