Comparison of Drainage Methods in Minimally Invasive Esophagectomy (DEMURE）
Comparison of the Application Effects of Different Drainage Modes in the Perioperative Period of Minimally Invasive Three-Field Radical Esophagectomy for Esophageal Cancer
Ruijin Hospital
75 participants
Apr 30, 2025
INTERVENTIONAL
Conditions
Summary
This RCT compares three drainage approaches after minimally invasive esophagectomy (chest tube + thoracic mediastinal drainage tube, thoracic, and abdominal mediastinal drainage tube) to evaluate perioperative outcomes, addressing current evidence gaps in pain and complication profiles.
Eligibility
Inclusion Criteria3
- Age ≥18 years
- Pathologically confirmed esophageal cancer requiring three-incision esophagectomy (cervical, thoracic, and abdominal incisions)
- ASA physical status class I-III
Exclusion Criteria4
- History of chronic pain or long-term use of analgesics prior to surgery
- Severe cardiopulmonary dysfunction (e.g., FEV1 \<50%)
- Coagulation disorders or patients undergoing reoperation
- Intraoperative findings of extensive pleural adhesions, combined resection of adjacent organs, or other conditions deemed by the investigator to warrant exclusion
Interventions
Transthoracic mediastinal drainage was performed for postoperative management of the patient.
Transperitoneal mediastinal drainage was performed for postoperative management of the patient.
Chest tube insertion combined with transthoracic mediastinal drainage was performed for postoperative management of the patient.
Locations(1)
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NCT07004634