Combined Blood Pressure Medication and Activity Scheduling for Low Mood

This study is investigating whether a blood pressure medication combined with a behavioral therapy technique (activity scheduling) can improve low mood and positive emotions in people who are feeling persistently down but do not have a severe depression diagnosis. **You may be eligible if...** - You are between 18 and 65 years old - You have self-reported low levels of positive mood - You have access to a computer with a reliable internet connection - You have normal or corrected vision and hearing - You have not taken antidepressants in the last 3 months **You may NOT be eligible if...** - You have a history of psychosis, bipolar disorder, or substance dependence - You are currently at clinical risk of suicide or have a history of suicide attempts - You are currently taking blood pressure or heart medication - You have very low blood pressure (below 90/60 mmHg) - Your depression score is severe (BDI-II score above 30) - You have a significant neurological disorder (e.g., epilepsy) Talk to your doctor to see if this trial is right for you.