Effects of Peripheral Magnetic Stimulation on Cortical Excitability in Healthy Individuals
Universidade Federal de Pernambuco
18 participants
Oct 1, 2022
INTERVENTIONAL
Conditions
Summary
This study investigates the immediate effects of different parameters (frequency, intensity, and pulse number) of peripheral magnetic stimulation (rPMS) on cortical excitability in healthy individuals. Using a randomized, double-blind crossover design, the research aims to identify optimal stimulation protocols for modulating neural activity. Outcomes include measurements of motor-evoked potentials (MEPs), intracortical inhibition (ICI), and facilitation (ICF). Findings may enhance non-invasive therapeutic strategies for neurological disorders.
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Interventions
Low-frequency stimulation (1 Hz) at 90% of resting motor threshold intensity, delivering a total of 2400 pulses.
High-frequency stimulation (10 Hz) at 90% of resting motor threshold intensity, totaling 2400 pulses.
High-frequency stimulation (25 Hz) at 90% of resting muscle threshold intensity, with 2400 pulses.
Low-frequency (1 Hz), at resting motor threshold intensity (100%) protocol delivering 2400 pulses.
High-frequency (10 Hz), at resting motor threshold intensity (100%) protocol delivering 2400 pulses.
High-frequency (25 Hz), at resting motor threshold intensity (100%) protocol delivering 2400 pulses.
Low-frequency (1 Hz), above resting motor threshold intensity (110%) protocol delivering 2400 pulses.
High-frequency (10 Hz), above resting motor threshold intensity (110%) protocol delivering 2400 pulses.
High-frequency (25 Hz), above resting motor threshold intensity (110%) protocol delivering 2400 pulses.
Locations(1)
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NCT07025759