RecruitingNot ApplicableNCT07034599

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.


Sponsor

Karlsburg Hospital

Enrollment

30 participants

Start Date

Oct 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.


Eligibility

Min Age: 18 Years

Inclusion Criteria1

  • All patients after implantation of a durable left ventricular assist device

Exclusion Criteria1

  • Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation

Interventions

DEVICENegative pressure ventilation

All participants are ventilated with negative pressure ventilation first

DEVICEpositive pressure ventilation

All participants are ventilated using positive pressure ventilation after negative pressure ventilation


Locations(1)

Klinikum Karlsburg

Karlsburg, Germany

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NCT07034599


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