Efficacy and Safety of Prepectoral Prosthesis Immediate One-Stage Breast Reconstruction Versus Two-Stage Expander/Prosthesis Reconstruction in Postoperative Adjuvant Radiotherapy Breast Cancer Patients: A Prospective, Single-Center, Cohort Study

This study compares two methods of breast reconstruction after mastectomy in women who also need radiation therapy: placing the implant in front of the chest muscle in one step (prepectoral) versus a two-step process using a temporary tissue expander first. **You may be eligible if...** - You are a woman between 18 and 70 years old - You have newly diagnosed breast cancer with no evidence of distant spread - You need radiation therapy after surgery - You are scheduled for a nipple-sparing or skin-sparing mastectomy **You may NOT be eligible if...** - You have had previous radiation to the chest - You have distant metastases - Your body shape or health status makes one-step reconstruction unsuitable Talk to your doctor to see if this trial is right for you.