RecruitingNot ApplicableNCT07041762

Rhomboid Intercostal Block With Sub-Serratus Plane Block Versus Erector Spinae Block

Analgesic Efficacy of Rhomboid Intercostal Block With Sub-Serratus Plane Block Versus Erector Spinae Block in Breast Cancer Surgery


Sponsor

Cairo University

Enrollment

80 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study compares two nerve block techniques-Rhomboid Intercostal with Sub-Serratus Plane Block versus Erector Spinae Plane Block-for pain relief after breast cancer surgery. It aims to determine which method provides better postoperative pain control, reduces opioid use, and improves recovery in patients undergoing modified radical mastectomy at the National Cancer Institute, Cairo University.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of nerve block techniques used to control pain after a modified radical mastectomy (breast removal surgery for cancer): the Rhomboid Intercostal with Sub-Serratus Plane Block versus the Erector Spinae Block. Both use local anesthetic injections in the back area to reduce post-surgical pain. The study wants to find which technique works better. **You may be eligible if...** - You are a female breast cancer patient scheduled for a modified radical mastectomy - You are between 18 and 65 years old - Your BMI is between 20 and 35 - You are in generally good pre-surgical health (ASA status II or III) **You may NOT be eligible if...** - You are under 18 or over 65 years old - Your BMI is below 20 or above 35 - You have a known allergy to local anesthetics or opioids - You have a history of chronic pain or psychological disorders - You have conditions that prevent regional anesthesia (such as bleeding disorders or skin infections at the injection site) - You decline to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURERhomboid Intercostal Block with Sub-Serratus Plane Block

Ultrasound-guided regional anesthesia combining two injections: Rhomboid Intercostal Block (20 mL of 0.25% bupivacaine injected between rhomboid major and intercostal space) Sub-Serratus Plane Block (20 mL of 0.25% bupivacaine injected between serratus anterior and ribs). Both performed 30-45 minutes before Modified Radical Mastectomy under general anesthesia.

PROCEDUREErector Spinae Plane Block

Ultrasound-guided regional block with 30 mL of 0.25% bupivacaine injected into the paraspinal plane at the T4-T5 level, between the erector spinae muscle and the transverse processes. Performed 30-45 minutes prior to general anesthesia for Modified Radical Mastectomy.


Locations(1)

National Cancer Institute - Cairo University

Cairo, Egypt

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NCT07041762


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