Rhomboid Intercostal Block With Sub-Serratus Plane Block Versus Erector Spinae Block
Analgesic Efficacy of Rhomboid Intercostal Block With Sub-Serratus Plane Block Versus Erector Spinae Block in Breast Cancer Surgery
Cairo University
80 participants
Jun 1, 2025
INTERVENTIONAL
Conditions
Summary
This study compares two nerve block techniques-Rhomboid Intercostal with Sub-Serratus Plane Block versus Erector Spinae Plane Block-for pain relief after breast cancer surgery. It aims to determine which method provides better postoperative pain control, reduces opioid use, and improves recovery in patients undergoing modified radical mastectomy at the National Cancer Institute, Cairo University.
Eligibility
Inclusion Criteria4
- Female breast cancer patients undergoing Modified Radical Mastectomy (MRM)
- ASA physical status II or III
- Age between 18 and 65 years
- Body Mass Index (BMI) \> 20 kg/m² and \< 35 kg/m²
Exclusion Criteria8
- Patient refusal
- ASA physical status IV
- Age \<18 years or \>65 years
- BMI \< 20 kg/m² or \> 35 kg/m²
- Known allergy or contraindication to local anesthetics or opioids
- History of psychological disorders or chronic pain
- Contraindications to regional anesthesia (e.g., coagulopathy, local infection, peripheral neuropathy)
- Severe respiratory, cardiac, hepatic, or renal disease
Interventions
Ultrasound-guided regional anesthesia combining two injections: Rhomboid Intercostal Block (20 mL of 0.25% bupivacaine injected between rhomboid major and intercostal space) Sub-Serratus Plane Block (20 mL of 0.25% bupivacaine injected between serratus anterior and ribs). Both performed 30-45 minutes before Modified Radical Mastectomy under general anesthesia.
Ultrasound-guided regional block with 30 mL of 0.25% bupivacaine injected into the paraspinal plane at the T4-T5 level, between the erector spinae muscle and the transverse processes. Performed 30-45 minutes prior to general anesthesia for Modified Radical Mastectomy.
Locations(1)
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NCT07041762