Mosunetuzumab for CLL MRD Clearance

This trial tests mosunetuzumab — a drug that helps the immune system find and destroy cancer cells — in people with chronic lymphocytic leukemia (CLL) who still have detectable cancer cells in their blood after completing standard treatment. The goal is to eliminate these remaining cancer traces and potentially achieve a deeper remission. **You may be eligible if...** - You have been diagnosed with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL) - You still have detectable cancer cells in your blood after finishing treatment (measurable residual disease) - You are in otherwise good general health - You meet blood count and organ function requirements **You may NOT be eligible if...** - You have active autoimmune disease requiring systemic treatment - You have a serious infection or uncontrolled illness - You have had prior treatment with certain immune therapies that may interfere - You have other significant health conditions that make participation unsafe Talk to your doctor to see if this trial is right for you.