Mavacamten to Aficamten Transition in Patients With Obstructive Hypertrophic Cardiomyopathy
Oregon Health and Science University
40 participants
May 5, 2026
INTERVENTIONAL
Conditions
Summary
This is an investigator-initiated two-center study. The goal of this study is to investigate the feasibility, safety and efficacy outcomes of a seamless transition from mavacamten to aficamten in patients with obstructive hypertrophic cardiomyopathy (oHCM).
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Patients will be switched from mavacamten to aficamten. Mavacamten will be stopped at enrollment, and aficamten started 2 weeks later.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT07600177