Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa
Centre Hospitalier de Saint-Denis
300 participants
Apr 11, 2025
OBSERVATIONAL
Conditions
Summary
This study looks at how well one antibiotic (monotherapy) works compared to two antibiotics (combination therapy) in treating bone infections caused by Pseudomonas aeruginosa. It includes 300 adult patients who had this type of infection confirmed by lab tests and medical imaging. The goal is to find out if using just one antibiotic is as effective as using two, while also looking at side effects, the need for more surgery, antibiotic resistance, and overall antibiotic use.
Eligibility
Plain Language Summary
Simplified for easier understanding
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Locations(1)
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NCT07056881