Osteomyelitis Clinical Trials

27 recruitingLast updated: May 21, 2026

There are 27 actively recruiting osteomyelitis clinical trials across 13 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 3. Top locations include Charlotte, North Carolina, United States, Lexington, Kentucky, United States, Hershey, Pennsylvania, United States. Updated daily from ClinicalTrials.gov.


Osteomyelitis Trials at a Glance

27 actively recruiting trials for osteomyelitis are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Charlotte, Lexington, and Hershey. Lead sponsors running osteomyelitis studies include BONESUPPORT AB, Biocomposites Ltd, and Rigshospitalet, Denmark.

Browse osteomyelitis trials by phase

About Osteomyelitis Clinical Trials

Looking for clinical trials for Osteomyelitis? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Osteomyelitis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Osteomyelitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Not Applicable

Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin.

Osteomyelitis
Biocomposites Ltd139 enrolled1 locationNCT07270380
Recruiting
Phase 2

A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

OsteomyelitisPressure Ulcer, Stage IV
Biocomposites Ltd60 enrolled9 locationsNCT06283979
Recruiting

CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure

Osteomyelitis
BONESUPPORT AB128 enrolled1 locationNCT06555848
Recruiting

Prospective Study of Sinonasal and Skull-base Tumours Management

Nasal NeoplasmNasal Neoplasm BenignSkull Base Neoplasms+3 more
University Medical Centre Ljubljana120 enrolled1 locationNCT05607888
Recruiting

INfectious DIsease REgistry BIObank

Bone and joint infectionsInfective EndocarditisCentral Nervous System Infections+4 more
IRCCS San Raffaele10,000 enrolled1 locationNCT06418048
Recruiting
Phase 4

Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot

Osteomyelitis - FootOsteomyelitis of Lower ExtremitiesOsteomyelitis of the Foot
Michael Garron Hospital1,418 enrolled3 locationsNCT07266753
Recruiting
Phase 4

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Osteomyelitis TibiaTibial FracturesOpen Tibia Fracture
Wake Forest University Health Sciences484 enrolled14 locationsNCT05421741
Recruiting

Reliability and Validation of the WB-MRI Radiological Score in CRMO

PediatricsChronic Recurrent Multifocal Osteomyelitis
IRCCS Azienda Ospedaliero-Universitaria di Bologna15 enrolled1 locationNCT07483853
Recruiting

Infrared Thermography for Diagnosis of Musculoskeletal Infections

Septic arthritisMusculoskeletal InfectionOsteomyelitis/Septic Arthritis
Sheffield Children's NHS Foundation Trust30 enrolled1 locationNCT07388017
Recruiting
Phase 3

Intramedullary Calcium Sulfate Antibiotic Depot

Osteomyelitis TibiaTibial FracturesOpen tíbia Fracture
Wake Forest University Health Sciences497 enrolled10 locationsNCT05766670
Recruiting
Phase 4

BonE and Joint Infections - Simplifying Treatment in Children Trial

Septic arthritisOsteomyelitisBone and Joint Infection+1 more
Murdoch Childrens Research Institute285 enrolled10 locationsNCT04538053
Recruiting

CERAMENT G Device Registry

Diabetic foot osteomyelitisChronic OsteomyelitisFracture Related Infection
BONESUPPORT AB100 enrolled3 locationsNCT06010433
Recruiting

Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa

OsteomyelitisPseudomonas aeruginosaBacterial Infections+1 more
Centre Hospitalier de Saint-Denis300 enrolled1 locationNCT07056881
Recruiting
Phase 4

Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections

Septic arthritisOsteomyelitis AcuteMethicillin Resistant Staphylococcus Aureus+6 more
Indiana University100 enrolled1 locationNCT06982105
Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Multiple Endocrine Neoplasia Type 1Multiple Endocrine Neoplasia Type 2Rare Disorders+337 more
Sanford Health20,000 enrolled2 locationsNCT01793168
Recruiting

Mirragen Diabetic Foot Ulcer Study

Diabetic Foot UlcerOsteomyelitis Chronic
The University of Texas Health Science Center at San Antonio20 enrolled1 locationNCT06598241
Recruiting

Initial Oral Antibiotics for Bone and Joint Infections in Children

Septic arthritisOsteomyelitis AcuteBone and Joint Infection+2 more
Rigshospitalet, Denmark100 enrolled1 locationNCT06827496
Recruiting
Not Applicable

Additional Hyperbaric Oxygen After Lower Extremity Amputation

OsteomyelitisDiabetes MellitusAmputation+6 more
Oslo University Hospital120 enrolled2 locationsNCT03594344
Recruiting

Fosfomycin I.v. for Treatment of Severely Infected Patients

OsteomyelitisEncephalitisSepsis+13 more
Infectopharm Arzneimittel GmbH1,000 enrolled50 locationsNCT02979951
Recruiting

CHronic Nonbacterial Osteomyelitis International Registry

Chronic Recurrent Multifocal OsteomyelitisChronic Nonbacterial Osteomyelitis
Seattle Children's Hospital2,000 enrolled1 locationNCT04725422