Osteomyelitis Clinical Trials

8 recruiting

Frequently Asked Questions

Common questions about Osteomyelitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 21 trials

Recruiting
Phase 4

Comparison of Oral Antibiotics For Bone Infections of the Leg and Foot

Osteomyelitis - FootOsteomyelitis of Lower ExtremitiesOsteomyelitis of the Foot
Michael Garron Hospital1,418 enrolled3 locationsNCT07266753
Recruiting
Phase 4

Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

Osteomyelitis TibiaTibial FracturesOpen Tibia Fracture
Wake Forest University Health Sciences484 enrolled14 locationsNCT05421741
Recruiting

Reliability and Validation of the WB-MRI Radiological Score in CRMO

PediatricsChronic Recurrent Multifocal Osteomyelitis
IRCCS Azienda Ospedaliero-Universitaria di Bologna15 enrolled1 locationNCT07483853
Recruiting
Phase 2

A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.

OsteomyelitisPressure Ulcer, Stage IV
Biocomposites Ltd60 enrolled7 locationsNCT06283979
Recruiting
Phase 3

Intramedullary Calcium Sulfate Antibiotic Depot

Osteomyelitis TibiaTibial FracturesOpen tíbia Fracture
Wake Forest University Health Sciences497 enrolled10 locationsNCT05766670
Recruiting

CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage Procedure

Osteomyelitis
BONESUPPORT AB128 enrolled1 locationNCT06555848
Recruiting

CERAMENT G Device Registry

Chronic OsteomyelitisFracture Related Infection
BONESUPPORT AB100 enrolled3 locationsNCT06010433
Recruiting

Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas Aeruginosa

OsteomyelitisPseudomonas Infections
Centre Hospitalier de Saint-Denis300 enrolled1 locationNCT07056881
Recruiting
Phase 4

Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections

Osteomyelitis AcuteMethicillin Resistant Staphylococcus Aureus
Indiana University100 enrolled1 locationNCT06982105
Recruiting

Mirragen Diabetic Foot Ulcer Study

Diabetic Foot UlcerOsteomyelitis Chronic
The University of Texas Health Science Center at San Antonio20 enrolled1 locationNCT06598241
Recruiting

Initial Oral Antibiotics for Bone and Joint Infections in Children

Osteomyelitis Acute
Rigshospitalet, Denmark100 enrolled1 locationNCT06827496
Recruiting
Not Applicable

Additional Hyperbaric Oxygen After Lower Extremity Amputation

OsteomyelitisDiabetes MellitusAmputation+6 more
Oslo University Hospital120 enrolled2 locationsNCT03594344
Recruiting

Fosfomycin I.v. for Treatment of Severely Infected Patients

OsteomyelitisEncephalitisSepsis+13 more
Infectopharm Arzneimittel GmbH1,000 enrolled50 locationsNCT02979951
Recruiting

Prospective Study of Sinonasal and Skull-base Tumours Management

Nasal NeoplasmNasal Neoplasm BenignSkull Base Neoplasms+3 more
University Medical Centre Ljubljana120 enrolled1 locationNCT05607888
Recruiting

CHronic Nonbacterial Osteomyelitis International Registry

Chronic Recurrent Multifocal OsteomyelitisChronic Nonbacterial Osteomyelitis
Seattle Children's Hospital2,000 enrolled1 locationNCT04725422
Recruiting
Not Applicable

Evaluation of the Efficiency of the Bone Substitute Cerament-G Locally Delivering Gentamicin in the Treatment of Chronic Osteomyelitis of Long Bones

Osteomyelitis Chronic
Hospices Civils de Lyon220 enrolled15 locationsNCT04805164
Recruiting
Not Applicable

RCT on Bioactive Glass S53P4 in Diabetic Foot Osteomyelitis in the Forefoot (DFORCT)

Osteomyelitis - Foot
ASST Ovest Milanese140 enrolled7 locationsNCT06388603
Recruiting

SAVE- Oral Antibiotics for Treatment of Vertebral Osteomyelitis

Osteomyelitis; Vertebra
Rigshospitalet, Denmark530 enrolled1 locationNCT06250023
Recruiting

Epidemiology and Management of invasive infections among people who Use drugs (EMU)

OsteomyelitisInjecting drug useBacteraemia+1 more
Monash University146 enrolled1 locationACTRN12622001173785
Recruiting

A single-arm feasibility trial evaluating a protein-based scaffold system with tissue transfer for the reconstruction of skull fractures

Salvage of failed calvarial reconstructionAcquired defect of the calvanium - trauma, malignancy or osteomyelitis
Princess Alexandra Hospital10 enrolled1 locationACTRN12620001171909