RecruitingPhase 2NCT07073794

Evaluating In Home Cancer Therapy Versus In Clinic Cancer Therapy in Black Men With Locally Advanced, Biochemically Recurrent and Metastatic Prostate Cancer

A Phase 2 Pragmatic Clinical Trial to Evaluate Administration of Cancer Therapy in the Patients' Homes Versus in Clinic in Black Men With Advanced or Metastatic Prostate Cancer


Sponsor

Mayo Clinic

Enrollment

38 participants

Start Date

Aug 27, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This phase II trial evaluates the impact of cancer therapy in the patients' home compared to in the clinic on safety, side effects, patient preference, and satisfaction in Black men with prostate cancer that has spread to nearby tissue or lymph nodes (locally advanced), that has increasing prostate-specific antigen after treatment (biochemically recurrent) or that has spread from where it first started (primary site) to other places in the body (metastatic). Typically drug-related cancer care is conducted at a medical center which causes patients to have to spend considerable time away from family, friends, and familiar surroundings. This separation may add to the physical, emotional, social, and financial burden for patients and their families during this difficult time in their lives. Therapy administered to a patient in the patients' residence in the comfort of familiar surrounding using Cancer Connected Access and Remote Expertise (CARE) Beyond Walls (CCBW) may help reduce psychological and financial distress, increase access to care and improve treatment compliance. Giving cancer therapy in the home compared in the clinic may be safe, tolerable and improve patient satisfaction with overall cancer care in Black men with locally advanced, biochemically recurrent or metastatic prostate cancer.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing home-based cancer treatment versus clinic-based cancer treatment in Black men with prostate cancer, to see which setting leads to better outcomes, satisfaction, and quality of life. **You may be eligible if...** - You are 18 years or older - You identify as Black or African American - You are a man with locally advanced, high-risk, biochemically recurrent, or metastatic prostate cancer - You are currently receiving or planning to start a standard-of-care treatment that is either FDA-approved or recommended in national cancer guidelines **You may NOT be eligible if...** - You are not receiving a qualifying standard-of-care treatment regimen - You do not identify as Black or African American - You are under 18 years old Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCancer Therapeutic Procedure

Given standard of care cancer treatment in clinic

DRUGCancer Therapeutic Procedure

Given standard of care cancer treatment in home

OTHERHealth Care Delivery

Receive in home cancer treatment with CCBW

OTHERQuestionnaire Administration

Ancillary studies


Locations(1)

Mayo Clinic in Florida

Jacksonville, Florida, United States

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NCT07073794


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