RecruitingPhase 4NCT07088146

Dexamethasone in Prolonging the Duration of Spinal Anesthesia Among Pregnant Patients

Role of Intravenous Dexamethasone in Prolonging the Duration of Sub-Arachnoid Block in Pregnant Patients Undergoing Lower Segment Cesarean Section


Sponsor

Rawalpindi Medical College

Enrollment

110 participants

Start Date

Jul 20, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Lower segment C section is one of the most commonly performed surgeries worldwide. It is performed in spinal anesthesia. During Spinal Anesthesia a local anesthetic drug is administered in a space surrounding spinal cord and it blocks nerves originating from spinal cord providing both anesthesia and analgesia. This technique avoids harmful exposure of drugs to the baby inside the womb of mother. However this technique provides anesthesia and analgesia of limited duration which can be prolonged by addition of drugs to patient management regimen. One such drug is Dexamethasone which is a steroid commonly administered in the peri-operative period.


Eligibility

Sex: FEMALEMin Age: 16 YearsMax Age: 40 Years

Inclusion Criteria2

  • American Society of Anesthesiologists (ASA) class: II and above.
  • Elective Cesarean section under Spinal Anesthesia.

Exclusion Criteria7

  • Gestational diabetes
  • Body mass index >35 kg/m2
  • Diabetes mellitus
  • Adrenal insufficiency
  • Chronically receiving steroids
  • Allergic to study medications
  • Sensory block level less than T4

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Interventions

DRUGDexamethasone

Immediately after sub-arachnoid block 8mg of Dexamethasone will be administered intravenously

DRUGPlacebo

2ml of Normal saline will be given intravenously immediately after administration of spinal anesthesia


Locations(1)

Benazir Bhutto Hospital Rawalpindi

Rawalpindi, Punjab Province, Pakistan

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NCT07088146


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